A multifunctional plasmonic chip for bacteria capture, imaging, detection, and <i>in situ</i> elimination for wound therapy

Gao, Xia; Wu, Haotian; Hao, Zhe; Ji, Xiangyi; Lin, Xiaodong; Wang, Shuo; Liu, Yaqing

doi:10.1039/d0nr00638f

Cited by 34 publications

(15 citation statements)

References 42 publications

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“…It also inactivates Gram-positive bacteria and Gram-negative bacteria in situ, which is of great significance in the field of human health examination and early clinical diagnosis (Figure 15a). [147] Zhou et al reported a new Raman tag 3,3'-diethylthiatricarbocyanine iodide Figure 15. a) Schematic of the multifunctional chip for bacterial capture, imaging, detection, and in situ inactivation of pathogen bacteria in vivo.…”

Section: Application Of Bacterial Detection In Clinical and Food Safetymentioning

confidence: 99%

“…It also inactivates Gram‐positive bacteria and Gram‐negative bacteria in situ, which is of great significance in the field of human health examination and early clinical diagnosis ( Figure a). [ 147 ] Zhou et al. reported a new Raman tag 3,3’‐diethylthiatricarbocyanine iodide (DTTC)‐conjugated gold–silver nanoshells (Au–Ag NSs) substrate that provided a non‐invasive and extremely high sensitive detection (down to 300 CFU mL −1 ).…”

Section: Application Of Bacterial Detection In Clinical and Food Safetymentioning

confidence: 99%

Section: Application Of Bacterial Detection In Clinical and Food Safetymentioning

confidence: 99%

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Bacteria Detection: From Powerful SERS to Its Advanced Compatible Techniques

et al. 2020

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The rapid, highly sensitive, and accurate detection of bacteria is the focus of various fields, especially food safety and public health. Surface-enhanced Raman spectroscopy (SERS), with the advantages of being fast, sensitive, and nondestructive, can be used to directly obtain molecular fingerprint information, as well as for the on-line qualitative analysis of multicomponent samples. It has therefore become an effective technique for bacterial detection. Within this progress report, advances in the detection of bacteria using SERS and other compatible techniques are discussed in order to summarize its development in recent years. First, the enhancement principle and mechanism of SERS technology are briefly overviewed. The second part is devoted to a label-free strategy for the detection of bacterial cells and bacterial metabolites. In this section, important considerations that must be made to improve bacterial SERS signals are discussed. Then, the label-based SERS strategy involves the design strategy of SERS tags, the immunomagnetic separation of SERS tags, and the capture of bacteria from solution and dye-labeled SERS primers. In the third part, several novel SERS compatible technologies and applications in clinical and food safety are introduced. In the final part, the results achieved are summarized and future perspectives are proposed.

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Section: Application Of Bacterial Detection In Clinical and Food Safetymentioning

confidence: 99%

Section: Application Of Bacterial Detection In Clinical and Food Safetymentioning

confidence: 99%

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Bacteria Detection: From Powerful SERS to Its Advanced Compatible Techniques

et al. 2020

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“…In this perspective, an interesting approach has been proposed by Liu and coworkers in two recent papers. PB nanoparticles [46] and Au@PB [47] core-shell nanostructures were decorated with vancomycin, a well-known antibiotic present in the WHO list of essential medicines. The binding of vancomycin on PBNP has a double function: it imparts an increased antibacterial and wound-healing effect when compared to bare PBNPs, and it can act as a targeting unit in the sensing of bacteria.…”

Section: Prussian Blue Doped With Traditional Antibioticsmentioning

confidence: 99%

Prussian Blue and Its Analogs as Novel Nanostructured Antibacterial Materials

2021

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Prussian blue is an ancient artificial pigment. Its biocompatibility and the possibility of synthesizing it in nanometric size stimulated the interest of the scientific community. Many uses of Prussian blue nanoparticles have been reported in the field of nanomedicine. More recently, interest into the potential application of Prussian blue nanoparticles as antibacterial agents has spread. Literature regarding Prussian blue and its analogs as antibacterial materials is still limited, but the number of papers has grown quickly over the last 2–3 years.

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“…Alternatively, a multifunctional gold chip was fabricated to perform the early diagnosis and photothermally ablate bacteria, which exhibited high bacterial capture efficiency and excellent photothermal bactericidal ability (98%) against Gram-positive and -negative bacteria. [236] Meanwhile, the gold chip was confirmed to be an effective repairing agent for promoting the wound healing in bacteria-infected mice in vivo. Reproduced with permission.…”

Section: More Anisotropic Gold Nanostructuresmentioning

confidence: 99%

Plasmonically Modulated Gold Nanostructures for Photothermal Ablation of Bacteria

Guan

Win

Yang

et al. 2020

Adv Healthcare Materials

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With the wide utilization of antibiotics, antibiotic‐resistant bacteria have been often developed more frequently to cause potential global catastrophic consequences. Emerging photothermal ablation has been attracting extensive research interest for quick/effective eradication of pathogenic bacteria from contaminated surroundings and infected body. In this field, anisotropic gold nanostructures with tunable size/morphologies have been demonstrated to exhibit their outstanding photothermal performance through strong plasmonic absorption of near‐infrared (NIR) light, efficient light to heat conversion, and easy surface modification for targeting bacteria. To this end, this review first introduces thermal treatment of infectious diseases followed by photothermal therapy via heat generation on NIR‐absorbing gold nanostructures. Then, the usual synthesis and spectral features of diversified gold nanostructures and composites are systematically overviewed with the emphasis on the importance of size, shape, and composition to achieve strong plasmonic absorption in NIR region. Further, the innovated photothermal applications of gold nanostructures are comprehensively demonstrated to combat against bacterial infections, and some constructive suggestions are also discussed to improve photothermal technologies for practical applications.

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A multifunctional plasmonic chip for bacteria capture, imaging, detection, and in situ elimination for wound therapy

Abstract: A multifunctional plasmonic gold chip is created to serve as a triple enhancer for PEF, SERS and NIR for bacteria analysis.

Cited by 34 publications

References 42 publications

Bacteria Detection: From Powerful SERS to Its Advanced Compatible Techniques

Bacteria Detection: From Powerful SERS to Its Advanced Compatible Techniques

Prussian Blue and Its Analogs as Novel Nanostructured Antibacterial Materials

Plasmonically Modulated Gold Nanostructures for Photothermal Ablation of Bacteria

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