2006
DOI: 10.2106/jbjs.e.00173
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A Multimodal Analgesia Protocol for Total Knee Arthroplasty

Abstract: This multimodal perioperative analgesia protocol that included infiltration of a local anesthetic offered improved pain control and minimal side effects to patients undergoing total knee arthroplasty. Our study also confirmed the safety of the protocol.

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Cited by 337 publications
(310 citation statements)
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“…There are some limitations to our study. First, we used the same protocol of multimodal analgesia for pain control in all patients [16,29]. However, we did not record morphine consumption or consider that in assessing pain.…”
Section: Discussionmentioning
confidence: 99%
“…There are some limitations to our study. First, we used the same protocol of multimodal analgesia for pain control in all patients [16,29]. However, we did not record morphine consumption or consider that in assessing pain.…”
Section: Discussionmentioning
confidence: 99%
“…Except for the study by Badner et al [3], studies using intraarticular injections alone failed to show a reduction of narcotic consumption after surgery [5,16,19,22]. Comparing PAI with narcotics alone, two studies [17,27] found decreased early postoperative pain and morphine consumption (Table 4). Comparing PAI with continuous femoral nerve block, Toftdahl et al [26] reported lower pain and morphine consumption in the PAI group on the first day postsurgery.…”
Section: Discussionmentioning
confidence: 99%
“…An estimated sample size of 27 in each group was needed to provide 80% power to detect a clinically meaningful difference of 15 mg morphine consumption from PCA during the first 48 hours [27] between the two groups with a SD of 19.4 mg and alpha error of 0.05.…”
Section: Methodsmentioning
confidence: 99%
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