A NAC Domain Protein Interacts with <i>Tomato leaf curl virus</i> Replication Accessory Protein and Enhances Viral Replication

Selth, Luke A.; Dogra, Satish C.; Rasheed, Madiha; Healy, Helen; Randles, J. W.; Rezaian, M. Ali

doi:10.1105/tpc.104.027235

Cited by 166 publications

(130 citation statements)

References 75 publications

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“…Additionally, NAC proteins have been implicated in disease defense and abiotic stress signaling. Several NAC proteins have been shown to interact with virus proteins [19][20][21], or to play direct roles in regulating pathogen defense [22]. Some NAC proteins were recently identified as abiotic stress regulators.…”

Section: Introductionmentioning

confidence: 99%

Dual function of Arabidopsis ATAF1 in abiotic and biotic stress responses

et al. 2009

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NAC family genes encode plant-specific transcription factors involved in diverse biological processes. In this study, the Arabidopsis NAC gene ATAF1 was found to be induced by drought, high-salinity, abscisic acid (ABA), methyl jasmonate, mechanical wounding, and Botrytis cinerea infection. Significant induction of ATAF1 was found in an ABA-deficient mutant aba2 subjected to drought or high salinity, revealing an ABA-independent mechanism of expression. Arabidopsis ATAF1-overexpression lines displayed many altered phenotypes, including dwarfism and short primary roots. Furthermore, in vivo experiments indicate that ATAF1 is a bona fide regulator modulating plant responses to many abiotic stresses and necrotrophic-pathogen infection. Overexpression of ATAF1 in Arabidopsis increased plant sensitivity to ABA, salt, and oxidative stresses. Especially, ATAF1 overexpression plants, but not mutant lines, showed remarkably enhanced plant tolerance to drought. Additionally, ATAF1 overexpression enhanced plant susceptibility to the necrotrophic pathogen B. cinerea, but did not alter disease symptoms caused by avirulent or virulent strains of P. syringae pv tomato DC3000. Transgenic plants overexpressing ATAF1 were hypersensitive to oxidative stress, suggesting that reactive oxygen intermediates may be related to ATAF1-mediated signaling in response to both pathogen and abiotic stresses.

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Section: Introductionmentioning

confidence: 99%

Dual function of Arabidopsis ATAF1 in abiotic and biotic stress responses

et al. 2009

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“…AL1 binding to a mitotic kinesin and histone H3 may also play a direct role in viral replication (Kong and Hanley-Bowdoin, 2002). The ability of AL3 to enhance viral DNA replication is mediated in part through its interaction with a host NAC1 transcription factor (Selth et al, 2005). The AL1 protein also binds to UBC9, a component of the plant sumoylation pathway (Castillo et al, 2004), but how this interaction contributes to infection is not clear.…”

mentioning

confidence: 99%

Geminivirus Infection Up-Regulates the Expression of Two Arabidopsis Protein Kinases Related to Yeast SNF1- and Mammalian AMPK-Activating Kinases

Shen¹,

Hanley‐Bowdoin²

2006

Plant Physiol.

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Geminivirus Rep-interacting kinase 1 (GRIK1) and GRIK2 constitute a small protein kinase family in Arabidopsis (Arabidopsis thaliana). An earlier study showed that a truncated version of GRIK1 binds to the geminivirus replication protein AL1. We show here both full-length GRIK1 and GRIK2 interact with AL1 in yeast two-hybrid studies. Using specific antibodies, we showed that both Arabidopsis kinases are elevated in infected leaves. Immunoblot analysis of healthy plants revealed that GRIK1 and GRIK2 are highest in young leaf and floral tissues and low or undetectable in mature tissues. Immunohistochemical staining showed that the kinases accumulate in the shoot apical meristem, leaf primordium, and emerging petiole. Unlike the protein patterns, GRIK1 and GRIK2 transcript levels only show a small increase during infection and do not change significantly during development. Treating healthy seedlings and infected leaves with the proteasome inhibitor MG132 resulted in higher GRIK1 and GRIK2 protein levels, whereas treatment with the translation inhibitor cycloheximide reduced both kinases, demonstrating that their accumulation is modulated by posttranscriptional processes. Phylogenetic comparisons indicated that GRIK1, GRIK2, and related kinases from Medicago truncatula and rice (Oryza sativa) are most similar to the yeast kinases PAK1, TOS3, and ELM1 and the mammalian kinase CaMKK, which activate the yeast kinase SNF1 and its mammalian homolog AMPK, respectively. Complementation studies using a PAK1/TOS3/ELM1 triple mutant showed that GRIK1 and GRIK2 can functionally replace the yeast kinases, suggesting that the Arabidopsis kinases mediate one or more processes during early plant development and geminivirus infection by activating SNF1-related kinases.

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“…MYB4 was found to be involved in drought, salt, UV, ozone, viruses, bacteria, and fungi stresses and represents a crucial knot in the cross-talk of stress signaling cascades through the activation of multiple components in rice (Vannini et al, 2006). The NAC domain protein could interact with leaf curl virus in tomato (Selth et al, 2005).…”

Section: Discussionmentioning

confidence: 99%

Spermidine affects the transcriptome responses to high temperature stress in ripening tomato fruit

Lin

Sun

Wang

et al. 2012

J. Zhejiang Univ. Sci. B

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Abstract:Objective: High temperature adversely affects quality and yield of tomato fruit. Polyamine can alleviate heat injury in plants. This study is aimed to investigate the effects of polyamine and high temperature on transcriptional profiles in ripening tomato fruit. Methods: An Affymetrix tomato microarray was used to evaluate changes in gene expression in response to exogenous spermidine (Spd, 1 mmol/L) and high temperature (33/27 °C) treatments in tomato fruits at mature green stage. Results: Of the 10 101 tomato probe sets represented on the array, 127 loci were differentially expressed in high temperature-treated fruits, compared with those under normal conditions, functionally characterized by their involvement in signal transduction, defense responses, oxidation reduction, and hormone responses. However, only 34 genes were up-regulated in Spd-treated fruits as compared with non-treated fruits, which were involved in primary metabolism, signal transduction, hormone responses, transcription factors, and stress responses. Meanwhile, 55 genes involved in energy metabolism, cell wall metabolism, and photosynthesis were down-regulated in Spd-treated fruits. Conclusions: Our results demonstrated that Spd might play an important role in regulation of tomato fruit response to high temperature during ripening stage.

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A NAC Domain Protein Interacts with Tomato leaf curl virus Replication Accessory Protein and Enhances Viral Replication

Cited by 166 publications

References 75 publications

Dual function of Arabidopsis ATAF1 in abiotic and biotic stress responses

Dual function of Arabidopsis ATAF1 in abiotic and biotic stress responses

Geminivirus Infection Up-Regulates the Expression of Two Arabidopsis Protein Kinases Related to Yeast SNF1- and Mammalian AMPK-Activating Kinases

Spermidine affects the transcriptome responses to high temperature stress in ripening tomato fruit

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