A nanotechnology-based new approach in the treatment of breast cancer: Biosynthesized silver nanoparticles using Cuminum cyminum L. seed extract

Nanotechnology emerged as a scientific innovation in the 21st century. Metallic nanoparticles (metal or metal oxide nanoparticles) have attained remarkable popularity due to their interesting biological, physical, chemical, magnetic, and optical properties. Metal-based nanoparticles can be prepared by utilizing different biological, physical, and chemical methods. The biological method is preferred as it provides a green, simple, facile, ecofriendly, rapid, and cost-effective route for the green synthesis of nanoparticles. Plants have complex phytochemical constituents such as carbohydrates, amino acids, phenolics, flavonoids, terpenoids, and proteins, which can behave as reducing and stabilizing agents. However, the mechanism of green synthesis by using plants is still highly debatable. In this report, we summarized basic principles or mechanisms of green synthesis especially for metal or metal oxide (i.e., ZnO, Au, Ag, and TiO2, Fe, Fe2O3, Cu, CuO, Co) nanoparticles. Finally, we explored the medical applications of plant-based nanoparticles in terms of antibacterial, antifungal, and anticancer activity.

show abstract

“…Cuminum cyminum L. [255], Punica granatum [256], Salvia hispanica L [257], Avicennia marina [258], and Tectona grandis [259]. 6.3.6.…”

Section: Synthesis Of Silver Nanoparticles Using Leaf Extracts: (2019-2020)mentioning

confidence: 99%

Green Synthesis of Metal and Metal Oxide Nanoparticles Using Different Plants’ Parts for Antimicrobial Activity and Anticancer Activity: A Review Article

et al. 2021

View full text Add to dashboard Cite

show abstract

“…For the green synthesis of silver nanoparticles, plants extracts have been also used as it offers many advantages and also does not require any complex process for the synthesis of AgNPs via plants extract and comparatively easy for large‐scale production (Ahmad et al, 2010; Ahmed et al, 2016; Al‐thabaiti et al, 2015; Ansari et al, 2016; Banerjee et al, 2014; Dinparvar et al, 2020; Hebbalalu et al, 2013; Hussain & Khan, 2014; Jain et al, 2009; Krishnaraj et al, 2010; Leela & Vivekanandan, 2008; Logeswari et al, 2015; MubarakAli et al, 2011; Prasad, 2014; Rahisuddin & Akrema, 2016; Song & Kim, 2009; Vijilvani et al, 2020). Mainly the parts of the plant used for the synthesis are leaves, root, stem, bark, flower and fruit (Meena et al, 2020).…”

Section: Organisms Used In Green Synthesis Of Nanoparticlesmentioning

confidence: 99%

A review on recent developments in the biosynthesis of silver nanoparticles and its biomedical applications

Arif

Uddin

2020

Med Devices & Sens

View full text Add to dashboard Cite

Green chemistry is the significant field of research as it offers simple, cost-effective, easy, biocompatible and eco-friendly methods for the synthesis of nanomaterials. With the development of nanotechnology, the synthesis of silver nanoparticles (AgNPs) has become important areas of research due to their various applications in industrial, pharmacological and medicinal fields as they exhibited good antibacterial, antifungal, antioxidant, anti-inflammatory, antiviral, anticoagulant, thrombolytic, cytotoxic and photocatalytic properties due to their chemical stability and good biocompatibility.How to cite this article: Arif R, Uddin R. A review on recent developments in the biosynthesis of silver nanoparticles and its biomedical applications.

show abstract

“…Essential oil from cumin was found more efficient than commercial insecticides, and it was proposed in innovative green formulations in crop protection against E. fetida and H. axyridis [ 11 ]. Several studies have suggested to develop nanoparticles based on cumin extracts for effective antleichmaniose [ 12 ] and antitumor activities [ 13 ]. Indeed, cuminaldehyde presents antinociceptive, antineuropathic and anti-inflammatory effects [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Biochemical Composition of Cumin Seeds, and Biorefining Study

et al. 2020

View full text Add to dashboard Cite

A new biorefinery approach has been developed in the present study, and applied on cumin (Cuminum cyminum) seeds as a potential source of phytochemicals of interest. Cumin is a popular spice used widely for its distinctive aroma. It is a rich reserve of both vegetable and essential oils. The biorefinery approach here focused on the evaluation of the influence of four different geographical origins (i.e., Lebanon, France, Algeria and Syria) on oil yield and quality in cumin seed, and on the valorization of remaining by-products by investigating their nutritional content and biological activity for the first time. Vegetable and essential oils were extracted, and their compositions were determined. Nutritional traits were also assessed. The delipidated and hydrodistillated cakes just as aromatic water were characterized for their fiber, sugar, protein, phenol and flavonoid contents. Antibacterial and antioxidant activities were also determined. Cumin seeds showed high contents in both vegetable and essential oils, proteins and sugars regardless their origin. Moreover, this Apiaceae species exhibited high levels of petroselinic fatty acid (an isomer of oleic acid) and sterols. Cakes and aromatic water also presented high levels of proteins, fibers, sugars and phenols. These residues revealed interesting antioxidant and antibacterial activities. These results emphasized the potential use of cumin in a biorefinery concept, with a multi-purpose industrial process. In addition, large differences were observed between the four geographical origins for phytochemical contents and compositions. These findings highlight the perspectives for developing selection programs for nutritional traits and industrial interests. All obtained results validate the health promoting effect of cumin composition as well as its industrial importance along with the residues.

show abstract

A nanotechnology-based new approach in the treatment of breast cancer: Biosynthesized silver nanoparticles using Cuminum cyminum L. seed extract

Cited by 66 publications

References 59 publications

Green Synthesis of Metal and Metal Oxide Nanoparticles Using Different Plants’ Parts for Antimicrobial Activity and Anticancer Activity: A Review Article

Green Synthesis of Metal and Metal Oxide Nanoparticles Using Different Plants’ Parts for Antimicrobial Activity and Anticancer Activity: A Review Article

A review on recent developments in the biosynthesis of silver nanoparticles and its biomedical applications

Biochemical Composition of Cumin Seeds, and Biorefining Study

Contact Info

Product

Resources

About