2019
DOI: 10.26650/istanbuljpharm.2019.19002
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A new approach for the synthesis of N,N’-bis(phenoxyacetyl)hydrazines

Abstract: This report is about an unexpected formation of N,N'-bis(substituted phenoxyacetyl) hydrazine derivatives. The reaction between N'-(4-ethylcyclohexylidene)phenoxyacetohydrazide with sulfanyl acids to obtain 4-thiazolidinones s, gave an unexpected product, N,N'-bis(phenoxyacetyl)hydrazine, with high purity instead of the expected cyclocondensation product. When repeating the reaction with p-toluenesulfonic acid under the same conditions, the reaction resulted in the same compound. This indicates that two molecu… Show more

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