Abstract:Sotolon (3‐hydroxy‐4,5‐dimethyl‐2(5H)‐furanone) has been synthezised both in racemic and enantioenriched forms by a short sequence involving intramolecular tandem isomerization‐aldolisation and tandem izomerization/Mannich reactions as key steps. Optically active Sotolon has been obtained by using (S)‐N‐tert‐butane sulfinimine as a chiral starting material.
The current study highlighted the significance of β-aminoketones as privileged biologically active molecules, recent synthetic strategies, and synthetic applications.
The current study highlighted the significance of β-aminoketones as privileged biologically active molecules, recent synthetic strategies, and synthetic applications.
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