A new approach for transversalis fascia reinforcement in Lichtenstein’s inguinal hernia repair

Abstract

Operations undertaken for inguinal hernia repair are the most common elective surgical procedures. According to the current guidelines, Lichtenstein's tension-free method is the gold standard for elective hernia operations. The most common types of implanted mesh are polypropylene and composite mesh. We herein present Lichtenstein's operation using a biological hemostatic mesh (Tachosil) used for transversalis fascia reinforcement, and our results after a 3-year follow-up period for 52 patients implanted with Tachosil mesh are reported. According to our results, the biological mesh can be safely implanted during hernia repair with the same recurrence rate and lower postoperative pain and complications compared to hernia repair with polypropylene mesh implantation.

The impact of IL-6 and IL-28B gene polymorphisms on treatment outcome of chronic hepatitis C infection among intravenous drug users in Croatia

“…IFN-λ interacts with a transmembrane receptor to induce a potent antiviral response (Donnelly & Kotenko, 2010; Fox, Sheppard & O’Hara, 2009; Li & Huang, 2007). The antiviral activity is mediated through the activation of the either JAK-STAT (IFN α, λ and γ) or MAPK (IFN α and λ) pathways (Arslani et al, 2013). There is a strong association of genetic variations in IL-28B gene with response to therapy (Ge et al, 2009; Suppiah et al, 2009; Tanaka et al, 2009), and with spontaneous HCV clearance (Duggal et al, 2013).…”

Peer Review #1 of "The impact of IL-6 and IL-28B gene polymorphisms on treatment outcome of chronic hepatitis C infection among intravenous drug users in Croatia (v0.1)"

“…IFN-λ interacts with a transmembrane receptor to induce a potent antiviral response (Donnelly & Kotenko 2010;Fox et al 2009;Li & Huang 2007). The antiviral activity is mediated through the activation of the either JAK-STAT (IFN α, λ and γ) or MAPK (IFN α and λ) pathways (Arslani et al 2013). There is a strong association of genetic variations in IL-28B gene with response to therapy (Ge et al 2009;Suppiah et al 2009;Tanaka et al 2009), and with spontaneous HCV clearance (Duggal et al 2013).…”

Wrapping colonic anastomoses: Omentoplasty versus a carrier­ bound fibrin sealant

“…14 Even though technical modifications have decreased the rate of leakage in colonic anastomosis, the high mortality and severe morbidity in patients suffering from anastomotic leakage justify the necessity for evaluation of additional methods for decreasing the rate of anastomotic failure in these operations. 15 Collagen-bound fibrin sealant sheets have recently been used in many aspects of surgery; for example: Hernia, 16 Gastro-intestinal, 17,18 ophthalmic, 19 gynecologic & obstetric, 20 renal, 21 vascular 22 and cardiac 23,24 surgeries; and many experimental animal studies proved its efficacy in securing GI anastomoses. [25][26][27] In 2010, Huh et al performed a prospective study involving 223 patients with rectal cancer who underwent laparoscopic resection.…”