A new catalyst for the synthesis of 2-substituted perimidines catalysed by FePO₄

Abstract

The reaction of 1,8-diaminonaphthalene with aromatic aldehydes gave 2-substituted perimidines in the presence of FePO 4 as a versatile, green and reusable catalyst at room temperature.

Chitosan hydrochloride mediated efficient, green catalysis for the synthesis of perimidine derivatives

“…The solid product was washed with ethanol and further dried in oven at 50°C under vacuum. The purified compounds were further characterized using the representative 1 H‐NMR and 13 C‐NMR, and for remaining compound, we compared their melting points with reported melting points …”

“…They are also used as dyes, catalyst, photochromic compounds, and antioxidants. Literature shows that there are several reports on the use of metal chlorides (RuCl 3 and BiCl 3 ), triflates (Ytterbium (III) triflate, a mild Lewis acid), Cu (NO 3 ) 2 , zeolite NaY, CMK‐5‐SO 3 H nanocatalyst, InCl 3 , BF 3 ‐H 2 O, and Zn (OAc) 2 .2H 2 O for synthesis of perimidine derivatives . Although these compounds have been synthesized efficiently, the reported methodology suffers major disadvantages such as long reaction time, use of nonreusability of catalyst, harsh conditions, and generation of side reactions.…”

“…Literature shows that there are several reports on the use of metal chlorides (RuCl 3 and BiCl 3 ), triflates (Ytterbium (III) triflate, a mild Lewis acid), Cu (NO 3 ) 2 , zeolite NaY, CMK-5-SO 3 H nanocatalyst, InCl 3 , BF 3 -H 2 O, and Zn (OAc) 2 .2H 2 O for synthesis of perimidine derivatives. [26][27][28][29][30] Although these compounds have been synthesized efficiently, the reported methodology suffers major disadvantages such as long reaction time, use of nonreusability of catalyst, harsh conditions, and generation of side reactions. We have investigated the effect of catalyst, catalyst loading, temperature, and solvents on the reaction rate catalyzed by chitosan hydrochloride to yield desired product.…”

Fe3O4@NCs/BF0.2: A magnetic bio‐based nanocatalyst for the synthesis of 2,3‐dihydro‐1H‐perimidines

“…The proposed mechanism for the synthesis of 2-phenyl-2,-3-dihydro-1H-perimidine in the presence of Fe 3 [22] 2 NSSA a (2 mg) r.t. EtOH 50 min 84 [7] 3 Cu(NO 3 ) 2 .6H 2 O (5 mol%) r.t. EtOH 10 min 83 [6] 4 CuY zeolite (0.002 g) r.t. EtOH 25 min 81 [9] 5 FePO 4 (0.01 g) r.t. EtOH 12 hr 80 [5] 6…”

“…A synthetic method for the preparation of perimidines is the condensation reaction of 1,8‐diaminonaphthalene with various carbonyl compounds such as carboxylic acids, anhydrides, acid halides, ketones, or aldehyde reagents . These compounds have been synthesized in the presence of various catalysts, such as, FePO 4 , Cu(NO 3 ) 2 ·6H 2 O, nanosilica sulfuric acid, NaY zeolite, nano‐CuY zeolite, N ‐bromosuccinamide, and CMK‐5‐SO 3 H …”