2002
DOI: 10.1186/1472-6750-2-8
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A new device for measurement of fibrin clot lysis: application to the Euglobulin Clot Lysis Time

Abstract: Background: Determination of clot lysis times on whole blood, diluted whole blood, plasma or plasma fraction has been used for many years to assess the overall activity of the fibrinolytic system. We designed a completely computerised semi-automatic 8-channel device for measurement and determination of fibrin clot lysis. The lysis time is evaluated by a mathematical analysis of the lysis curve and the results are expressed in minute (range: 5 to 9999). We have used this new device for Euglobulin Clot Lysis Tim… Show more

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Cited by 38 publications
(24 citation statements)
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“…Euglobulin Clot Lysis Time-The euglobulin fraction was prepared as described by Zouaoui Boudjeltia et al (43). Briefly, 300 l of acetic acid (0.025%) and 3.6 ml of deionized water were added to 400 l of pooled human plasma.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Euglobulin Clot Lysis Time-The euglobulin fraction was prepared as described by Zouaoui Boudjeltia et al (43). Briefly, 300 l of acetic acid (0.025%) and 3.6 ml of deionized water were added to 400 l of pooled human plasma.…”
Section: Methodsmentioning
confidence: 99%
“…Clot formation was started by adding 100 l (1.5 units/ml) of thrombin. ECLT was measured by a semi-automatic method using a "Lysis Timer" device (43).…”
Section: Methodsmentioning
confidence: 99%
“…Patients were 49 consecutive patients (31 nonseptic and 18 septic). Plasma fibrinolysis was assessed by the euglobulin clot lysis time (ECLT) at ICU admission [ 3 ].…”
Section: Methodsmentioning
confidence: 99%
“…To study the fibrinolysis process, a euglobulin fraction (a plasma fraction) was placed on the cell surface, and the clotting was induced by thrombin addition. The lysis time was measured in a newly designed apparatus and expressed in minutes [ 3 ].…”
Section: Methodsmentioning
confidence: 99%