A new dihydrochalcone from dragon's blood, red resin ofDracaena cochinchinensis

Abstract

A new dihydrochalcone, 4'-hydroxy-4,2'-dimethoxy-dihydrochalcone, was isolated from Chinese dragon's blood, the red resin of Dracaena cochinchinensis. Its structure was established by spectrum analysis.

Flavonoids and their glycosides, including anthocyanins

“…The structures and sources of 15 new mono-C-glycosylflavones (383)(384)(385)(386)(387)(388)(389)(390)(391)(392)(393)(394)(395)(396)(397) published in the 2007-2009 period are listed in Table 3. 38,259, A 6-C-b-glucopyranoside (383) of the relatively simple flavone, chrysin 7-methyl ether (5-hydroxy-7-methoxyflavone) has been isolated from extracts of the aerial parts of the aromatic herb, Sphaeranthus indicus (Asteraceae), which is well known as a medicinal plant in India.…”

Flavonoid oligomers from Chinese dragon’s blood, the red resins of Dracaena cochinchinensis

“…3 Previous studies showed that the resin contains mainly of phenolic compounds, as well as several steroids and aliphatic acids. [30][31][32][33][34][35][36][37][38] In our continuing studies on Chinese dragon's blood, five new flavonoid oligomers namely cochinchinenins D-H (1-5) were further isolated and identified from the red resin of D. cochinchinesis, in addition to the known biflavonoid, cinnabarone (6), and a mixture of two known biflavonoids, socotrin-4'-ol (7) and homoisosocotrin-4'-ol (8). Their structures were elucidated on the basis of detailed spectroscopic analysis.…”

Flavonoids and Stilbenoids of the Genera Dracaena and Sansevieria: Structures and Bioactivities

“…Flavans (Figure 10): 7,4'-dihydroxy-8-methylflavan (45) [43,44,49], 4,4′-dihydroxy-2,6dimethoxydihydrochalcone [47,48], (2R)-7,4'-dihydroxy-5-methoxy-8-methylflavan [49], 5,4'dihydroxy-7-methoxy-6-methylflavan (46) [44,46,49], 7,4'-dihydroxy-3'-methoxyflavan [49], 7,4'dihydroxyflavan (47) [46,49], (-)-7-hydroxy-4′-methoxyflavan [43,[45][46][47], (2S)-7,4′-dihydroxy-8methylflavan (48) [46,47], (2S)-5,4′-dihydroxy-7-methoxy-8-methylflavan [47], (2R)-4′-hydroxy-7methoxy-8-methylflavan [47], and 6,4'-dihydroxy-7-methoxy-8-methylflavan [46]. Homoisoflavans and meta-homoisoflavans (Figure 11): (3R)-7,4′-dihydroxy-5,8-dimethoxyhomoisoflavan [(3R)-dracaeconolide B] (49) [49] (Figure 11) (3R)-7,4'-dihydroxy-8-methoxyhomoisoflavan (50) [48,49,53], (3R)-7,4′-dihydroxyhomoisoflavan (51) [45,46,48,49], (3R)-7,4'dihydroxy-5-methoxyhomoisoflavan (52) [42,46,48,49], 7,4'-dihydroxyhomoisoflavan (53) [43,44], (3R)-7,4′-dihydroxy-6-methoxyhomoisoflavan [52], 6,4'-dihydroxy-7-methoxyhomoisoflavan (54) [43,…”

“…homoisoflavan (50) [48,49,53], (3R)-7,4′-dihydroxyhomoisoflavan (51) [45,46,48,49], (3R)-7,4'dihydroxy-5-methoxyhomoisoflavan (52) [42,46,48,49], 7,4'-dihydroxyhomoisoflavan (53) [43,44], (3R)-7,4′-dihydroxy-6-methoxyhomoisoflavan [52], 6,4'-dihydroxy-7-methoxyhomoisoflavan (54) [43,46], (3R)-6,4'-dihydroxy-8-methoxyhomoisoflavan [49], 7,3′-dihydroxy-8,4′-dimethoxyhomoisoflavan [48], 4′-hydroxy-7,8-dimethoxyhomoisoflavan [48], 4′-hydroxy-5,7-dimethoxyhomoisoflavan [48], (7R,12bR)-7,10-dihydroxy-4,11-dimethoxydracaenone (55) [52], (7S,12bS)-11-hydroxy-1,10-dimethoxydracaenone (56) [52], (7S,12bS)-10,11-dihydroxy-1-methoxydracaenone (57) [52], 10hydroxy-11-methoxydracaenone (58) [52], 10,11-dihydroxydracaenone C (59) [44], and 4'-hydroxy-7,8-methylenedioxyhomoisoflavan (23) [46,48]. Flavonoid dimers and trimers (Figures 12 and 13): cochinchinenenes A-D (structures 60,63-65 in Figure 11) [44,47,53], cochinchinenenes E (66) and F (61) [43], cochinchinenenes G (67) and H (62) [44], "cochinchinenene G" (68) [42], (2R)-8-methylsocotrin-4′-ol (69) [47], cochinchinenin [44], cochinchinenin B (75 [44,47]…”