A new ent-labdane diterpenoid from Andrographis paniculata

Zou, Qiong Yu; Li, Na; Dan, Chun; Deng, Wen; Peng, Shu Lin; Ding, Li

doi:10.1016/j.cclet.2010.05.002

Cited by 14 publications

(5 citation statements)

References 5 publications

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“…A total of 135 compounds, including 40 flavonoids, 82 terpenes (diterpene glucoside, diterpenoids, diterpenes dimer, and triterpenoid), 3 steroids, and 10 other compounds were isolated and identified from A. paniculata by chromatographic methods. Most have been studies for different biological activities [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ]. The chemical structures of the isolated compounds from A. paniculata are shown in Figures 1 , 2 , and 3 and Figure S1.…”

Section: Andrographis Paniculata (Burmf) Neesmentioning

confidence: 99%

Chemical constituents and their biological activities from Taunggyi (Shan state) medicinal plants

Aminah

Tun

Kristanti

et al. 2021

Heliyon

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Medicinal plants are essential aspects of readily available primary healthcare remedies. Phytochemical constituents of medicinal plants cover a broad variety of chemical fields to explore medicines. This review highlights selected empirical data on traditional uses, phytochemistry, and pharmacological properties of Taunggyi medicinal plants, Andrographis paniculata, Physalis peruviana, and Cassia fistula. Historically, these plants have been used for many infections and diseases in Taunggyi. More than 361 chemical compounds have been isolated and identified from the selected plants. Some of the chemical constituents have substantial pharmacological properties. It is clear that these herbs have significant potential for useful natural supplements in many contemporary diseases. Thus, the aim of this review compiles an ethnobotanical survey and documentation of medicinal plants in Taunggyi (Myanmar). This review will also inspire Myanmar researcher's to further investigate the potential of these plants in their future work into new compound and new drugs.

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Section: Andrographis Paniculata (Burmf) Neesmentioning

confidence: 99%

Chemical constituents and their biological activities from Taunggyi (Shan state) medicinal plants

Aminah

Tun

Kristanti

et al. 2021

Heliyon

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“…: molecular weight. References : Arifullah ¶ et al 2013 [ 141 ]; Chen * et al 2006 [ 144 ]; Chen # et al 2008 [ 138 ]; Chen ~ et al 2014 [ 142 ]; Fujita § et al 1984 [ 145 ]; Ji β et al 2005 [ 135 ]; Liu æ et al 2008 [ 136 ]; Matsuda ¤ et al 1994 [ 18 ]; Pramanick ¢ et al 2006 [ 146 ]; Rao £ et al 2004 [ 147 ]; Reddy ¥ et al 2003 [ 148 ]; Reddy œ et al 2005 [ 80 ]; Seth ‡ et al 2010 [ 149 ]; Shen † et al 2006 [ 134 ]; Sule © et al 2011 [ 121 ]; Sule ® et al 2012 [ 123 ]; Wang ¬ et al 2009 [ 139 ]; Wu ø et al 2008 [ 72 ]; Xu $ et al 2010 [ 150 ]; Zhou þ et al 2008 [ 151 ]; Zou ð et al 2010 [ 152 ]. …”

Section: Figurementioning

confidence: 99%

Andrographis paniculata(Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology

Hossain

Urbi

Sule

et al. 2014

The Scientific World Journal

282

180

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As aboriginal sources of medications, medicinal plants are used from the ancient times. Andrographis paniculata is one of the highly used potential medicinal plants in the world. This plant is traditionally used for the treatment of common cold, diarrhoea, fever due to several infective cause, jaundice, as a health tonic for the liver and cardiovascular health, and as an antioxidant. It is also used to improve sexual dysfunctions and serve as a contraceptive. All parts of this plant are used to extract the active phytochemicals, but the compositions of phytoconstituents widely differ from one part to another and with place, season, and time of harvest. Our extensive data mining of the phytoconstituents revealed more than 55 ent-labdane diterpenoids, 30 flavonoids, 8 quinic acids, 4 xanthones, and 5 rare noriridoids. In this review, we selected only those compounds that pharmacology has already reported. Finally we focused on around 46 compounds for further discussion. We also discussed ethnobotany of this plant briefly. Recommendations addressing extraction process, tissue culture, and adventitious rooting techniques and propagation under abiotic stress conditions for improvement of phytoconstituents are discussed concisely in this paper. Further study areas on pharmacology are also proposed where needed.

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“…The methanol and aqueous extracts of the leaves of A. paniculata from different locations as well as andrographolide and 14-deoxy-11, 12-didehydroandrographolide isolated exhibited lipid peroxidation inhibition in Srague Dawley rats and free radical scavenging activities against DPPH. The lipid peroxidation inhibition activity varied from 55.6% to 63.9% and 33.78% to 33.77% for methanol and water extracts, respectively, showing that the activity of the methanol extracts were higher and significantly different (P<0.05) from that of the water extract. The methanol extract exhibited free radical scavenging activity ranging from 45.67% to 53.82%.…”

Section: Anti-oxidant Activitymentioning

confidence: 99%

Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology

Okhuarobo

Falodun

Erharuyi

et al. 2014

Asian Pacific Journal of Tropical Disease

219

112

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A new ent-labdane diterpenoid from Andrographis paniculata

Cited by 14 publications

References 5 publications

Chemical constituents and their biological activities from Taunggyi (Shan state) medicinal plants

Chemical constituents and their biological activities from Taunggyi (Shan state) medicinal plants

Andrographis paniculata(Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology

Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology

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