A new epirubicin biosensor based on amplifying DNA interactions with polypyrrole and nitrogen-doped reduced graphene: Experimental and docking theoretical investigations

Khodadadi, Arash; Faghih-Mirzaei, Ehsan; Karimi-Maleh, Hassan; Abbaspourrad, Alireza; Agarwal, Shilpi; Gupta, Vinod Kumar

doi:10.1016/j.snb.2018.12.164

Cited by 257 publications

(80 citation statements)

References 43 publications

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“…Compared to other approaches, the electrochemical approaches exhibited some advantages such as enhanced sensitivity and selectivity. Thus, there is substantial focus on developing a straightforward, expeditious, cost-efficient, and sensitive electrochemical approach to detect analytes [14][15][16][17][18][19][20][21][22][23][24][25]. Due to the exceptional characteristics of the nanoparticles, they have been used in various industries.…”

Section: Original Research Articlementioning

confidence: 99%

Voltammetric determination of zolpidem by using glassy carbon electrode modified with Ag/ZnO nanoplates

Aflatoonian

Alizadeh

Rayeni

2020

Eurasian Chem. Commun.

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Zolpidem is an imidazopyridine derivative, non-benzodiazepine and sedative-hypnotic medicine. It is a widely prescribed medication in adults used for the short-term treatment of a sleep problem called insomnia and frequent awakenings. In this work, the zolpidem was determined using Ag/ZnO nanoplates modified glassy carbon electrode (Ag-ZnO/GCE). Electrochemical behavior of the zolpidem was investigated by differential pulse voltammetry (DPV), chronoamperometry (CHA), and cyclic voltammetry (CV) using the Ag-ZnO/GCE. The results revealed that, the current responses of the zolpidem improved significantly due to the high catalytic activity and electron transfer reaction of nanoplates. The linear range of zolpidem was found to be from 0.1 µM to 500.0 µM with the detection limit of 0.03 µM. In addition, this original sensor showed numerous benefits such as reproducibility, high stability, and rapid response (20 s).

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Section: Original Research Articlementioning

confidence: 99%

Voltammetric determination of zolpidem by using glassy carbon electrode modified with Ag/ZnO nanoplates

Aflatoonian

Alizadeh

Rayeni

2020

Eurasian Chem. Commun.

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“…The combination of the functional components to attain nanocomposite materials has gained growing attention, as such nanocomposites permit graceful amalgamation of chemical and physical properties, synergistic effects and multiple functions of individual components . The carbon‐based composite materials are striking for various applications because their outstanding chemical, mechanical, thermal and electric properties . The composite materials based on graphene and its derivatives possess unique properties such as chemical stability, low toxicity, biocompatibility, and flexibility for surface functionalization .…”

Section: Introductionmentioning

confidence: 99%

Application of GO/COF as a novel, efficient and recoverable catalyst in the Knoevenagel reaction

Monehzadeh

Rafiee

2020

Applied Organom Chemis

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Hybrid composite based on graphene oxide (GO) and covalent organic framework (COF) [GO/COF] was developed via a simple solvothermal method, at which GO was applied as a platform to load COF based on melamine and terephthaldehyde. The synthesized hybrid nanocomposite was characterized by FT‐IR, XRD, EDX and SEM techniques. Morphological analyses carried out by SEM confirm the successful growth of COF over GO. Then, the resultant composite was employed as an amazing and cost‐effective catalyst in the condensation of several aldehydes with malononitrile and produced the corresponding coupling products in high yields (up to 84%) at room temperature under solvent‐free conditions with an amount of catalyst, 15 mg in a very short reaction time of 10 min. The catalyst could be reused without a noteworthy drop in catalytic activity at least eight times. The use of GO/COF catalyst outcomes under mild reaction conditions in very short reaction time, exceptional catalytic activity, high recyclability and an easy work‐up process for the Knoevenagel condensation.

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“…The fundamental idea in the present work is based on DNA hybridization and target sequence detection via the spectrophotometric method. For this purpose, ssDNA can uncoil to expose its bases, whereas dsDNA has a stable double-helix geometry that always presents the negatively charged phosphate backbone [ 12 , 13 , 14 , 15 ]. Conferring to the results of present study, the engineered genosensor show simple structure with high sensitivity, stability, and high selectivity.…”

Section: Introductionmentioning

confidence: 99%

DNA based biosensing of Acinetobacter baumannii using nanoparticles aggregation method

Bahavarnia

Pashazadeh-Panahi

Hasanzadeh

et al. 2020

Heliyon

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Acinetobacter baumannii is the main cause of nosocomial infections in blood, urinary tract, wounds and in lungs leading to pneumonia. Apart from its strong predilection to be the cause of serious illnesses in intensive care units. Herein, we present a specific and sensitive approach for the monitoring of Acinetobacter baumannii genome based on citrate capped silver nanoparticles (Cit-AgNPs) using spectroscopic methods. In this study, (5ʹ SH-TTG TGA ACT ATT TAC GTC AGC ATG C3ʹ) sequence was used as a probe DNA (pDNA) of Acinetobacter baumannii . Then, complementary DNA (cDNA) was used for hybridization. After the hybridization of pDNA with cDNA, target DNA (5ʹ GCA TGC TGA CGT AAA TAGTTC ACA A 3ʹ) was recognized and detected using turn-on fluorescence bioassay. After the hybridization of pDNA with cDNA, the target DNA was successfully measured in optimum time of 2 min by spectrophotometric techniques. Moreover, the selectivity of designed bioassay was evaluated in the presence of two mismatch sequences and excellent differentiation was obtained. 1 Zepto-molar (zM) of low limit of quantification (LLOQ) was achieved by this genosensor. The present study paved the way for quick (2 min) and accurate detection of Acinetobacter baumannii , which can be a good alternative to the traditional methods. Current study proposed a novel and significant diagnostic test towards Acinetobacter baumannii detection based on silver nanoparticles aggregation which has the capability of being a good alternative to the traditional methods. Moreover, the proposed genosensor successfully could be applied for the detection of other pathogens.

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A new epirubicin biosensor based on amplifying DNA interactions with polypyrrole and nitrogen-doped reduced graphene: Experimental and docking theoretical investigations

Cited by 257 publications

References 43 publications

Voltammetric determination of zolpidem by using glassy carbon electrode modified with Ag/ZnO nanoplates

Voltammetric determination of zolpidem by using glassy carbon electrode modified with Ag/ZnO nanoplates

Application of GO/COF as a novel, efficient and recoverable catalyst in the Knoevenagel reaction

DNA based biosensing of Acinetobacter baumannii using nanoparticles aggregation method

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