A new era: Speckle tracking echocardiography and cardiomyopathies

Aksu, Uğur; Uzun, M.

doi:10.1002/jcu.23327

Cited by 1 publication

(1 citation statement)

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“…A typical left ventricular myocardium has three layers: endocardial myocardium, midwall myocardium and epicardial myocardium ( 6 ). The current speckle-tracking imaging (STI) technology studies mainly focus on the overall systolic function of the heart, while there are few studies on the role of the left ventricular three-layer myocardium ( 7 , 8 ).…”

Section: Introductionmentioning

confidence: 99%

Experimental research on the evaluation of left ventricular systolic function by layered speckle tracking before and after berberine treatment in a cardiac hypertrophy rat model

Luo¹,

Kou²,

Su³

et al. 2023

Cardiovasc Diagn Ther

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Background: To evaluate the effect of berberine (BBR) intervention on left ventricular hypertrophy and systolic function in rats by ultrasound layered strain imaging and cardiac hypertrophy model.Methods: Eighty healthy male Sprague-Dawley (SD) rats were randomly divided into four groups: group A (normal saline control group), group B [isoproterenol (ISO) induced model group], group C (BBR hydrochloride 5 mg/kg + ISO group) and group D (BBR hydrochloride 10 mg/kg + ISO group).Echocardiography was performed on days 1, 7 and 14, respectively. The myocardial tissue was taken for pathological examination. The key proteins of Rho/ROCK signaling pathway were quantified by immunohistochemical staining.Results: On day 7, compared with group A, peripheral strain values of the subendocardium and middle myocardium of rats in groups B, C and D were significantly decreased. The absolute value of circumferential strain (CS) in subendocardium and middle myocardium in group B was significantly lower than that in

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Section: Introductionmentioning

confidence: 99%