Communication between people is a basic social skill used to exchange information. It is often used for self-express and to meet basic human needs, such as the need for closeness, belonging, and security. This process takes place at different levels, using different means, with specific effects. It generally means a two-way flow of information in the immediate area of contact with another person. When people are communicating using the same language, the flow of information is much easier compared to the situation when two people use two different languages from different language families. The process of social communication with the deaf is difficult as well. It is therefore essential to use modern technologies to facilitate communication with deaf and non-speaking people. This article presents the results of work on a prototype of a glove using textronic elements produced using a physical vacuum deposition process. The signal from the sensors, in the form of resistance changes, is read by the microcontroller, and then it is processed and displayed on a smartphone screen in the form of single letters. During the experiment, 520 letters were signed by each author. The correctness of interpreting the signs was 86.5%. Each letter was recognized within approximately 3 s. One of the main results of the article was also the selection of an appropriate material (Velostat, membrane) that can be used as a sensor for the proposed application solution. The proposed solution can enable communication with the deaf using the finger alphabet, which can be used to spell single words or the most important key words.