A new iridoid glucoside from the Thai medicinal plant, Morinda elliptica Ridl

Noiarsa, Pawadee; Ruchirawat, Somsak; Otsuka, Hideaki; Kanchanapoom, Tripetch

doi:10.1007/s11418-006-0003-0

Cited by 10 publications

(5 citation statements)

References 9 publications

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“…However, there are a few reports on the presence of other types of compounds, particularly anthraquinones [6] and triterpenoids [7,8]. As part of our further continuing studies on Rubiaceous plants [9][10][11][12][13], we investigated the chemical constituents of this plant collected from Thailand. This paper describes the isolation and identification of ten polar constituents, including eight iridoid glucosides (1)(2)(3)(4)(5)(6)(7)(8) The dried whole plants of O. corymbosa (1.7 kg) were macerated with MeOH.…”

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confidence: 99%

Chemical constituents from Oldenlandia corymbosa L. of Thai origin

et al. 2007

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From the whole plants of Oldenlandia corymbosa of Thai origin, ten compounds have been isolated and elucidated as geniposide, 6 alpha-hydroxygeniposide, scandoside methyl ester (6 beta-hydroxygeniposide), asperulosidic acid, deacetylasperuloside, asperuloside, 10-O-benzoylscandoside methyl ester, 10-O-p-hydroxybenzoylscandoside methyl ester, (+)-lyoniresinol-3 alpha-O-beta-glucopyranoside, and rutin. Their structures were determined on the basis of spectroscopic data.

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Chemical constituents from Oldenlandia corymbosa L. of Thai origin

et al. 2007

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“…The Rubiaceae family is known for the production of alkaloids, iridoids, and anthraquinones (YOUNG et al, 1996), and flavonoids have been isolated from species of this family (LOPES et al, 2004, CARDOSO et al, 2005PINTO et al, 2008). Noiarsa et al (2006) identified 18 substances from the aerial parts of Spermacoce laevis Roxb. including flavonoids and iridoids, the latter being designated as a chemotaxonomic marker for species of the Rubeaceae family.…”

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confidence: 99%

Phytochemistry and larvicidal activity of Spermacoce latifolia Aubl. (Rubiaceae) in the control of Aedes aegypti L. (Culicidae)

et al. 2015

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ABSTRACT:In the search for alternative ways to control Aedes aegypti with minimal environmental impact and in a manner that preserves human health, this study sought to evaluate the larvicidal effect of the invasive and antioxidant Spermacoce latifolia plant by performing a phytochemical study. Phytochemical screenings were done according to characterization reactions and thin layer chromatography. Phenolics compounds content (Folin-Ciocalteu's) and flavonoids (AlCl 3 ) spectrophotometric was performed, and the antioxidant activity was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH). The phytochemical results revealed the presence of phenolic, flavonoid, tannin, steroid, free triterpene, coumarin, and alkaloid compounds. The content of total phenols (TPs) (482.7 ± 1.8 mg mgGA g -1 ) and flavonoids (165.4 ± 1.5 mg QE g -1 ) accounted for the antioxidant activity of 150 µg mL -1 methanolic extract. In the proposed bioassays, groups of 25 third-stage larvae were challenged at different concentrations of plant crude extract (1.0, 0.5, 0.25, and 0.1 mg mL -1 ) of weight per volume in four replicates. In multiple concentration tests, the concentrations were selected to range from 0 % to 100 % mortality after 24 hours of contact with the solution. Toxicity was defined as the inhibition or total inactivity of the larvae. It was concluded that the methanol extract had an LC 50 of 0.625 mg mL -1 , indicating its potential use as a larvicide against A. aegypti and linking its activity to its phenolic and flavonoid components.

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“…The remaining compounds were identified as asperulosidic acid (2), 12 daphylloside (3), 13 asperuloside (4), 13 (1R, 6R,9R) 6,9,11-trihydroxy-4-megastigmen-3-one (7), 4-epiborreriagenin (8), 14 trans-phytol (9), 15 ursolic acid lactone (10), 17 3β-hydroxyurs-12-en-28-al (11), and ursolic acid (12) 16 (see Figure 1). Their structures were established on the basis of spectral and chemical evidence, which were in good agreement with those reported in literature.…”

Section: Notesmentioning

confidence: 99%