“…Hydrodynamic cavitation in microfluidic devices occurs when the fluid flow experiences a considerable static pressure drop when it passes through a flow restrictive element inside a microchannel. In this regard, different geometries (micro-orifices, 15 micro-Venturis, 28,64 micro-diaphragms, 28,64 micro-pillar, 65 micro-steps 46 ), functional surfaces (hydrophilic or hydrophobic, 50 roughen or patterned 66 ), working fluids (isotropic or anisotropic, 67 pure or impure, 28,68 mixtures 29 ) were utilized to characterize various micro-scale cavitation flow patterns. In a pioneering study, Mishra et al 15 developed the first microfluidic device to study micro-scale cavitation using water as the working fluid.…”