A New Method for the Synthesis of Phenanthridine Compounds

Abstract

5-Methoxyphenanthridin-6(5H)-ones reacted with aryl Grignard reagents to afford phenanthridine compounds. The method has the advantages of mild reaction conditions with good yields and provides a new synthetic procedure for the phenanthridine derivatives. However, the products were phenanthridin-6(5H)-ones when alkyl magnesium bromide reacted with 5-methoxyphenanthridin-6(5H)-ones.

Trifluoromethylated hydrazones and acylhydrazones as potent nitrogen-containing fluorinated building blocks

“…The use of difluoromethylating and trifluoromethylating reagents is a popular approach applied to prepare di/trifluoromethyl-containing molecules [8][9][10][11][12][13][14][15][16][17][18]. Also the reaction of diverse di/trifluoromethyl-containing building blocks offers another mainstream approach to introducing fluorine.…”