A New Method of Reporting Data on Reproduction and Lactation in the Mouse

Mirone, Leonora; Panzarella, Frank P.; Cerecedo, Leopold R.

doi:10.1126/science.108.2797.139

Cited by 9 publications

(7 citation statements)

References 5 publications

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“…Therefore the pups survived the period which is usually the one with the highest death incidence (Mirone et al, 1948;Potgieter and Wilke, 1997). As to the period between day 13 and weaning (18 days of life), this is characterized by low, and often null, mortality rate (Iturrian and Fink, 1968;Potgieter and Wilke, 1997) which agrees with the results found in the present work (Table 2).…”

Section: Discussionsupporting

confidence: 90%

“…The high and extremely similar index of lactation of both groups observed in the present study corresponds to those described in previous works with a low mortality rate from 4 to 12 days of age (Mirone et al, 1948). Mirone et al (1948) and Potgieter and Wilke (1997) have stated that the rate of mortality during this period can reach values of around 9%. Potgieter and Wilke (1997) have found a mortality rate of 1.4% and 9.5% in mice of the B6AKF1 and AKR strains, respectively.…”

Section: Lactationsupporting

confidence: 92%

“…In this study, the mortality rate was extremely low up to the first four days of age, a fact that agrees with the results described by other workers (Iturrian and Fink, 1968). However, other reports (Mirone et al, 1948;Potgieter and Wilke, 1997) have shown higher mortality rates during this period. Potgieter and Wilke (1997) have found extreme variation in the mortality rate up to the fourth day of age in different strains varying from 20.7 to 69.6% under standard housing conditions (non-enriched), similar to the ones of the present work, especially in what concerns the bedding conditions.…”

Section: Lactationmentioning

confidence: 52%

“…The grounds of the cages were covered with 2 to 4 days post partum, and only 9% of deaths occur during the lactation period (Mirone et al, 1948). The number of pups alive on day 4 was, then, chosen as an indicator of pup viability (Potgieter and Wilke, 1997).…”

Section: Growth Ratementioning

confidence: 99%

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Development and reproductive performance of Swiss mice in an enriched environment

et al. 2009

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The present study investigated the effects of environment enrichment on the development and reproductive performance of an outbred Swiss strain. Physical enrichment consisted of free access of animals to tubular devices of different shapes and sizes. The development evaluation was done by monitoring growth rate during 39 days, from weaning (21 days) to the onset of sexual maturity (60 days of age). Over five consecutive gestations (105 days), the following variables were monitored: litter size, number of animals born alive; number of pups alive at 12 hours and on days 4, 9, 12, 15 and 18; number of animals weaned per litter; average weight of litters on days 4, 9, 12, 15 and 18. The reproductive performance was then evaluated using the inclusion of these variables in the indices of gestation and birth, viability, lactation, survival success, mating success and production. The results showed that the environmental enrichment did not influence, in a significant way, the evaluated parameters. However, there is no reason to deprive the animals from an enriched environment where they can develop their natural instinctive behaviour and guarantee health and well-being.Keywords: environmental enrichment, development, reproductive performance, mice. Desenvolvimento e performance reprodutiva de camundongos Swiss em ambiente enriquecidoResumo O presente estudo investigou efeitos do enriquecimento ambiental sobre o desenvolvimento e a performance reprodutiva de camundongos outbred da linhagem Swiss. O enriquecimento teve como base o livre acesso dos animais a dispositivos tubulares de tamanhos e formas diferentes. A avaliação do desenvolvimento a partir da taxa de crescimento decorreu por um período de 39 dias, desde o desmame (21 dias) até os 60 dias de vida (maturidade sexual). Durante cinco gestações consecutivas (105 dias), foram registradas as seguintes variáveis: média do tamanho da ninhada, nú-mero de animais nascidos vivos; número de filhotes vivos em 12 horas, e nos dias 4, 9, 12, 15 e 18; número de animais desmamados por ninhada; e a média do peso dos filhotes nos dias 4, 9, 12, 15 e 18. A performance reprodutiva foi então avaliada a partir da inclusão dessas variáveis nos índices de gestação e nascimento, viabilidade, lactação, sucesso de sobrevivência, sucesso de acasalamento e produção. Os resultados obtidos mostraram que o enriquecimento ambiental não influenciou significativamente no desenvolvimento e na performance reprodutiva de camundongos da linhagem Swiss para nenhum dos parâmetros avaliados. Contudo, não há motivo para privar os animais de um ambiente enriquecido onde possam desenvolver seu comportamento instintivo natural e, consequentemente, viver com saúde e bem-estar.Palavras-chave: enriquecimento ambiental, desenvolvimento, performance reprodutiva, camundongo.

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Section: Discussionsupporting

confidence: 90%

Section: Lactationsupporting

confidence: 92%

Section: Lactationmentioning

confidence: 52%

Section: Growth Ratementioning

confidence: 99%

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Development and reproductive performance of Swiss mice in an enriched environment

et al. 2009

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“…The following variables were measured: Mirone et al 7 demonstrated that 91 % of all litter deaths occur during the first 4 days post partum, whereas only 9 % of deaths occur during the lactation period. The number of young alive on day 4 was therefore chosen as an indicator of pup viability.…”

Section: Animalsmentioning

confidence: 99%

Effect of different bedding materials on the reproductive performance of mice

Potgieter

Wilke²

1997

J. S. Afr. Vet. Assoc.

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Vermiculite, pine shavings and unbleached eucalyptus pulp contact-bedding were compared using the number of litters and individuals born and weaned, mortality rates at different stages of the lactation period, and the weight increase of pups as evaluation indices for bedding quality. These bedding materials exerted different effects on the reproductive performance of the same mouse strain. The same is true for the effect of a specific bedding material on different mouse strains. These effects are most pronounced during the first 4 days of life. As a whole, the results demonstrated that eucalyptus pulp was the better bedding type, followed by pine shavings and vermiculite. The latter material had a detri-mental effect on the mating success of AKR mice

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Multigeneration Reproduction Studies

Collins

1978

Research Procedures and Data Analysis

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A New Method of Reporting Data on Reproduction and Lactation in the Mouse

Cited by 9 publications

References 5 publications

Development and reproductive performance of Swiss mice in an enriched environment

Development and reproductive performance of Swiss mice in an enriched environment

Effect of different bedding materials on the reproductive performance of mice

Multigeneration Reproduction Studies

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