A new method of sutureless microvascular anastomoses using a thermosensitive poloxamer and cyanoacrylate: An experimental study

Qassemyar, Q.; Michel, G.

doi:10.1002/micr.22381

Cited by 12 publications

(19 citation statements)

References 21 publications

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“…Regardless of the suturing method, restoration of the cylindrical structure of the vessel ends is a crucial element for the success of microvascular anastomosis. Indwelling or temporary stents, 1-6 cuffs, 10,11 and biodegradable filler 12,13 that avoid collapse of the vessel lumen have been reported previously. The notion of temporary stents has long been suggested.…”

Section: Discussionmentioning

confidence: 99%

Sutureless Microvascular Anastomosis using Intravascular Stenting and Cyanoacrylate Adhesive

Aizawa

Kuwabara

Kubo

et al. 2017

J reconstr Microsurg

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Section: Discussionmentioning

confidence: 99%

Sutureless Microvascular Anastomosis using Intravascular Stenting and Cyanoacrylate Adhesive

Aizawa

Kuwabara

Kubo

et al. 2017

J reconstr Microsurg

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“…Contrary to protein-based adhesives, which poses a high risk of penetrating the vascular lumen, cyanoacrylates have been shown to avoid penetration and embolization in the area of anastomosis (Aizawa et al, 2018;Liang et al, 2019). The use of VIVO also showed no differences in vessel blood flow and 100% patency during One aspect that prevents adhesive penetration and vessel collapse during polymerization is the use of intraluminal devices (Aizawa et al, 2018;Davis et al, 2016;Heitzer, Mohlhenrich, et al, 2021;Qassemyar & Michel, 2015;Saegusa et al, 2017). On the other hand, devices such as stents are associated with an increased risk of stenosis and thrombosis leading to devastating consequences for the affected patients (Yoon & Jones, 2016).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the long‐term results of vascular anastomosis using polyurethane adhesive and shape‐memory stent in the rat carotid artery model

et al. 2022

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Introduction:In free flaps, 5%-10% of complications are related to failure of sutured vascular anastomoses. Adhesive-based microvascular anastomoses are potential alternatives but are associated with failure rates of 70% in research studies. VIVO is a new adhesive with slow biodegradation within 6 months that has shown a 100% patency rate in research studies over 2 h observation time but long-term patency has not been evaluated. The authors hypothesize that VIVO will enable a reliable microvascular procedure comparable to sutured anastomoses over a 28-day period. Materials and Methods:The right common carotid artery of 60 male Sprague Dawley rats, $450 g, were used for microvascular end-to-end anastomosis. VIVO was applied with reduced sutures with a temporary catheter in one group and in the other with a custom-shaped memory stent. Anastomoses with eight interrupted sutures served as control. All groups were n = 20. Anastomosis time and bleeding were recorded for each procedure. Doppler flowmetry was performed 20 min, 1, 10, and 28 days postoperatively. Postmortem toluidine staining was used for semi-quantitative analysis of stenosis, thrombosis, necrosis, and aneurysm formation by histologic evaluation. Results:No occlusion was detected 20 min and 1 day postoperative, and after 28 days of observation in all anastomoses. The anastomosis time of the VIVO with catheter group was about 32% significantly faster than the VIVO with stent group. In the VIVO group with stent, the bleeding time was $80% shorter than in the control group with 2.1 ± 0.3 and VIVO with catheter 2.0 ± 0.5 (p ≤ .001 each). Minor and nonsignificant stent-associated thrombus formation and stent-typical intraluminal stenosis were detected exclusively in the VIVO with stent group. Conclusion:Within the limitations of a rat study, the use of VIVO in anastomosis showed promising results. VIVO with catheter was found to be advantageous.

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“…Temporary stent may be dissolve, which lysis immediately after fi nishing of anastomosis procedure as gels [14]. Non dissolved temporary stent, which put during anastomosis technique and removed before closure of line of anastomosis, Figure 2A: Both needles were passed from inside both femoral artery ends to pierce the artery wall and tissue brining the both stent ends on the skin where fi xed on skin for 2 weeks.…”

Section: Discussionmentioning

confidence: 99%

Closed removable thread vascular anastomosis stent (Lasheen Vascular Stent)

Lasheen¹

2019

J Surg Surgical Res

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Background: Vascular anastomosis is a most common and important part of many reconstructive transplant procedures. Venous anastomosis can be done by using coupling devices. In arterial anastomosis still the suture method is the main method, which is time consuming, need much experience, and associated by many complications specially with small arteries (microanastomosis). This study offers new type of stent (Lasheen vascular stent) for vascular anastomosis.Methods: This experimental study included 7 Egyptian native dogs. Under general anesthesia, the femoral artery was exposed and cut, then re-anastomosis by using thread vascular stent of suitable caliber. Where one end of stent passed from the lumen of distal end of femoral artery and passed through the tissue to appear on skin. Other end of stent passed from the lumen of proximal end of femoral artery through the tissue to appear on skin. Four sutures were taken to approximate two femoral ends on stent. Then, the wound closed in its layers with stent in its position and both stent ends were fi xed on skin. After, two weeks the stent was removed by traction on both stent ends to change the stent to thread and come out of body. Results:The mean time to put the stent in right position was 10 minutes. The prophylactic dose of antithrombotic drug given for three days and antiplatelet aggregation drug for 15 days. All anastomosis were clearly patent by clinical observation and duplex scanning if needed during period of follow up (3 months). No leakage during procedure or hematoma after stent removal were observed. Conclusion:Lasheen vascular stent for vascular anastomosis is rapid , less time consumed, has short learning curve and good results, and with no special complications.Citation: Lasheen AE (2019) Closed removable thread vascular anastomosis stent (Lasheen Vascular Stent). J Surg Surgical Res 5(2): 071-073.

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A new method of sutureless microvascular anastomoses using a thermosensitive poloxamer and cyanoacrylate: An experimental study

Abstract: This sutureless method of micro-anastomosis seems to be easy to learn and require lower time than conventional sutures. However, this technique needs further investigations over the coming years to prove long-term reliability.

Cited by 12 publications

References 21 publications

Sutureless Microvascular Anastomosis using Intravascular Stenting and Cyanoacrylate Adhesive

Sutureless Microvascular Anastomosis using Intravascular Stenting and Cyanoacrylate Adhesive

Evaluation of the long‐term results of vascular anastomosis using polyurethane adhesive and shape‐memory stent in the rat carotid artery model

Closed removable thread vascular anastomosis stent (Lasheen Vascular Stent)

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