A new methoxylated flavone from Lonicera hypoglauca and its chemotaxonomic significance

Yao, Caiyun; Song, Zhijun; Ruan, Li-Jun; Yan, Bing-Xiong; Wu, Qinghua; He, Lili; Wu, Yun-Qiu; Liu, Xihui; Peng, Yu-De; Jin, Miao

doi:10.1016/j.bse.2021.104279

Cited by 5 publications

(2 citation statements)

References 21 publications

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“…Compound 10 , a methoxylated flavone, contains a 2′,4′,5′-trisubstituted B ring, a motif rarely encountered in nature. It was isolated from the stems and leaves of Lonicera hypoglauca [ 25 ]. Compounds 11–14 were isolated from Fuzhuan brick tea, produced from the leaves of Camellia sinensis .…”

Section: Isolation Of Novel Flavonoids Isoflavonoids and Neoflavonoidsmentioning

confidence: 99%

“…From the isolates, compounds 1 , 10 , 27–34 , 55 , 79 , 81 , 148 , 227 , 228 , 248 , and 249 were not tested for unspecified reasons [ 19 , 25 , 31 , 38 , 41 , 60 , 76 , 79 ]. Additionally, compound 82 was not tested due to the putative inactivity of flavanonols in the antigen-induced degranulation assay in RBL-2H3 cells [ 42 ].…”

Section: Bioactivities Of Flavonoids Isoflavonoids and Neoflavonoidsmentioning

confidence: 99%

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Perplexing Polyphenolics: The Isolations, Syntheses, Reappraisals, and Bioactivities of Flavonoids, Isoflavonoids, and Neoflavonoids from 2016 to 2022

Umer

Shamim

Khan

et al. 2023

Life

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Flavonoids, isoflavonoids, neoflavonoids, and their various subcategories are polyphenolics–an extensive class of natural products. These compounds are bioactive and display multiple activities, including anticancer, antibacterial, antiviral, antioxidant, and neuroprotective activities. Thus, these compounds can serve as leads for therapeutic agents or targets for complex synthesis; they are coveted and routinely isolated, characterized, biologically evaluated, and synthesized. However, data regarding the compounds’ sources, isolation procedures, structural novelties, bioactivities, and synthetic schemes are often dispersed and complex, a dilemma this review aims to address. To serve as an easily accessible guide for researchers wanting to apprise themselves of the latest advancements in this subfield, this review summarizes seventy-six (76) articles published between 2016 and 2022 that detail the isolation and characterization of two hundred and forty-nine (249) novel compounds, the total and semisyntheses of thirteen (13) compounds, and reappraisals of the structures of twenty (20) previously reported compounds and their bioactivities. This article also discusses new synthetic methods and enzymes capable of producing or modifying flavonoids, isoflavonoids, or neoflavonoids.

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Section: Isolation Of Novel Flavonoids Isoflavonoids and Neoflavonoidsmentioning

confidence: 99%

Section: Bioactivities Of Flavonoids Isoflavonoids and Neoflavonoidsmentioning

confidence: 99%

Perplexing Polyphenolics: The Isolations, Syntheses, Reappraisals, and Bioactivities of Flavonoids, Isoflavonoids, and Neoflavonoids from 2016 to 2022

Umer

Shamim

Khan

et al. 2023

Life

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The influence of different drying methods on bioactive components of Eucommia ulmoides Oliver male flower and the comprehensive assessment for industrial application

Zheng

et al. 2022

Industrial Crops and Products

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Genus Lonicera: New drug discovery from traditional usage to modern chemical and pharmacological research

Xie

Jiang

et al. 2022

Phytomedicine

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A new methoxylated flavone from Lonicera hypoglauca and its chemotaxonomic significance

Cited by 5 publications

References 21 publications

Perplexing Polyphenolics: The Isolations, Syntheses, Reappraisals, and Bioactivities of Flavonoids, Isoflavonoids, and Neoflavonoids from 2016 to 2022

Perplexing Polyphenolics: The Isolations, Syntheses, Reappraisals, and Bioactivities of Flavonoids, Isoflavonoids, and Neoflavonoids from 2016 to 2022

The influence of different drying methods on bioactive components of Eucommia ulmoides Oliver male flower and the comprehensive assessment for industrial application

Genus Lonicera: New drug discovery from traditional usage to modern chemical and pharmacological research

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