In practice, picture hesitant fuzzy sets (PHFSs) combining the picture fuzzy sets (PFSs) and hesitant fuzzy sets (HFSs) are suitable to represent more complex multi-criteria decision-making (MCDM) information. The power heronian (PH) operators, which have the merits of power average (PA) and heronian mean (HM) operators, are extended to the environment of PHFSs in this article. First, some algebraic operations of picture hesitant fuzzy numbers (PHFNs), comparative functions and distance measure are introduced. Second, two novel operators, called as picture hesitant fuzzy weighted power heronian (PHFWPH) operator and picture hesitant fuzzy weighted geometric power heronian (PHFWGPH) operator, are defined. Meanwhile, some desirable characteristics and special instances of two operators are investigated as well. Third, a novel MCDM approach applying the proposed PH operators to handle PHFNs is explored. Lastly, to indicate the effectiveness of this novel method, an example regarding MCDM problem is conducted, as well as sensitivity and comparison analysis.