A New Perspective towards Diagnosis of Sleep Apnea: Isoprene Detection Using PSSA-g-PANI based SAW Sensor

Abstract

Sleep apnea; Sensor; Exhaled breath; Isoprene Cellular metabolic changes triggered by Obstructive Sleep Apnea Syndrome (OSAS) are detected invasively by detecting isoprene as a biomarker of OSAS in the breath. When falling asleep, isoprene level begins to increase above 3 ppm. Therefore, monitoring isoprene levels in exhaled breath under normal conditions may provide a non-invasive method to detect, monitor, and control sleep disorders such as sleep apnea. In this study, PSSA-g-PANI based SAW gas sensors were prepared and tested against isoprene gas. Sensor measurements reveal that PSSA-g-PANI based SAW type sensor detected (1-150) ppm isoprene gas with high sensitivity and thus PSSA-g-PANI based SAW type sensor may enable monitor and control of sleep apnea.