SummaryThis paper proposes a true random number generator (TRNG) based on a successive approximation register (SAR) analog‐to‐digital converter (ADC). A top‐plate sampling SAR ADC structure and a new MSB‐isolation switch scheme (MISS) are combined to achieve low‐power operation and small area occupancy at the same time. When the SAR ADC has completed its conversion, a secondary firing of the comparator measures the remaining signal. This 1‐bit quantized residue serves as the true random sequence, thus eliminating the need for extra circuitry in the TRNG. A 65‐nm prototype of the proposed TRNG was found to occupy an area of 0.012 mm2 and successfully passed all the National Institute of Standards and Technology (NIST) tests without post‐processing. It achieved a figure‐of‐merit of 0.244 pJ/bit for a 1 Mb/s random sequence with a 0.8‐V power supply. Its resilience to power noise injection attacks was also verified.