A new simultaneous derivatization and microextration method for the determination of memantine hydrochloride in human plasma

Jing, Shao-Jun; Li, Qinglian; Jiang, Ye

doi:10.1016/j.jchromb.2015.09.016

Cited by 13 publications

(7 citation statements)

References 24 publications

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“…Thirty-two out of the 41 publications included studies mentioned to have used ionic strength as one of the optimized parameters [5,24,28,[30][31][32][33][34][36][37][38][39] [41][42][43][44][45][46][47][48][49][51][52][53][54][55][56][57][58][59]61]. The salting-out effect is non-predictable and can either increase the extraction efficiency or decrease it due to the unpredictable effects on physical-chemical properties of the transition film present in the interface [1,15].…”

Section: Ionic Strengthmentioning

confidence: 99%

“…The salting-out effect is non-predictable and can either increase the extraction efficiency or decrease it due to the unpredictable effects on physical-chemical properties of the transition film present in the interface [1,15]. Eighteen of the studies that optimized the ionic strength decided not to use the salting-out technique in the final method [24,28,30,32,34,36,37,42,43,48,49,[51][52][53]56,57,59] due to either the negative impact of increased salt concentration on the extraction, or the lack of effect of it; and 14 of them [5,31,33,38,39,41,[44][45][46][47]54,55,58,61] decided to use the salting-out effect to improve extraction. All the studies that employed the salting-out effect, with exception of three [38,54,55], used sodium chloride.…”

Section: Ionic Strengthmentioning

confidence: 99%

“…All studies that used derivatization [26,33,53,54] concluded that intube/ in-situ derivatization -where derivatization happens within the walls of the fiber during the extraction -can be used instead of the traditional derivatization procedure (where derivatization takes place in a separate vial). Kramer et al [26] compared both derivatization methods and obtained poorer extraction efficiencies with in-tube derivatization; the reason being the mild temperature and short time employed by the authors, who justified the lower performance stating that the ease and speed of the method compensates for this decrease.…”

Section: Derivatizationmentioning

confidence: 99%

See 2 more Smart Citations

A review of the application of hollow-fiber liquid-phase microextraction in bioanalytical methods – A systematic approach with focus on forensic toxicology

Venson

Korb

Cooper

2019

Journal of Chromatography B

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Over the past three decades, many studies employing hollow-fiber liquid-phase microextraction (HF-LPME) bioanalytical methods have been published. The basic mechanism of extraction relies on the migration of the analytes through a liquid membrane sustained in the pores of the walls of a porous hollow fiber, and from there into an acceptor phase present in the lumen of the fiber. The mass transfer occurs by passive diffusion and it can be enhanced by using a carrier or applying an electrical potential across the phases. This type of extraction method presents many advantages over classical techniques, such as high preconcentration factor, clean extracts, and a green chemistry approach. Due to its advantages, and considering that no study systematically compiled the characteristics of the published methods in one single accessible source of information, the aim of this systematic review is to assess the data regarding bioanalytical methods, compile, and analyse the studies published until up to October of 2017. The data source used for the systematic review were Pubmed, Web of Science, and Science Direct, and 171 studies were included in the final review by two independent reviewers, resulting in a reliable and accessible source of information about bioanalytical methods employing HF-LPME.

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Section: Ionic Strengthmentioning

confidence: 99%

Section: Ionic Strengthmentioning

confidence: 99%

Section: Derivatizationmentioning

confidence: 99%

See 1 more Smart Citation

A review of the application of hollow-fiber liquid-phase microextraction in bioanalytical methods – A systematic approach with focus on forensic toxicology

Venson

Korb

Cooper

2019

Journal of Chromatography B

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“…Direct UV absorption and fluorescence analysis of memantine is challenging due to absence of chromophoric groups and the weak UV absorbance of the primary amine group. Derivatization reactions were proposed to impart measurable characteristics to mematine to enable UV, fluorescence and liquid chromatographic quantification [2][3][4][5][6][7][8][9][10]. Unfortunately, however, derivatization reactions involve highly reactive compounds that require high precautions and special safety measures.…”

Section: Introductionmentioning

confidence: 99%

3D spongy-like Au film for highly stable solid contact potentiometric ion selective electrode: application to drug analysis

Hussien

Derar

2019

SN Appl. Sci.

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Potentiometric ion selective electrodes with simple design and high potential stability are required for in-line process, clinical and quality control analysis. The objective of this work is to develop a high-surface-area Au nanostructure solidcontact (SC) platform for high stable ion selective electrode for drug analysis. Memantine, a pharmaceutical compound prescribed for Alzheimer's disease, with challenging measurable analytical characteristics, was selected as a model for this purpose. Internal solid-contact with a high surface area was prepared by direct electrochemical deposition of Aunanostructures onto a Pt electrode (500 µm diameter and 3 mm long). The proposed design combines the small size with the high surface area that is necessary for stable potential response. Cyclic voltammetry, impedance electrochemical spectroscopy and chronopotentiometry were used to evaluate electrochemical properties of the Au film. The Au-nanostructure SC electrode was coated with a membrane cocktail containing a lipophilic ion exchanger. The electrode exhibited a Nernstian response (58.5 ± 1 mV/decade) to memantine over a wide concentration range (1 × 10 −5-1 × 10 −2 M). The electrode showed high potential stability (0.03 µV/s), wide pH working range (3.0-8.0) and high selectivity to memantine log k pot i,j ≤ −2.38. The electrode was applied for direct determination of memantine in pharmaceutical dosage form, human urine and surface water with high accuracy (± 2%) and precision (RSD ≤ 1.5%).

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“…To apply UV/VIS or fluorescence HPLC detection of memantine, the derivatization step is required. Fluorescence detection has been used after precolumn derivatization using o‐phthaldialdehyde (OPA) , 4‐fluoro‐7‐nitro‐2,1,3‐benzoxadiazole , (2‐naphthoxy)acetyl chloride , dansyl chloride , fluorescamine , 4‐(4,5‐diphenyl‐1H‐imidazol‐2‐yl)benzoyl chloride , and 9‐fluorenylmethyl chloroformate . The RP‐HPLC using UV detection was applied for ME derivative with anthraquinone‐2‐sulfonyl chloride , 1‐fluoro‐2,4‐dinitrobenzene , 9‐fluorenylmethyl chloroformate , phenoxy acetyl chloride , and (2‐napthoxy)acetyl chloride .…”

Section: Introductionmentioning

confidence: 99%

Optimization of o‐phtaldialdehyde/2‐mercaptoethanol postcolumn reaction for the hydrophilic interaction liquid chromatography determination of memantine utilizing a silica hydride stationary phase

Douša

Pivoňková

Sýkora

2016

J of Separation Science

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A rapid procedure for the determination of memantine based on hydrophilic interaction chromatography with fluorescence detection was developed. Fluorescence detection after postcolumn derivatization with o-phtaldialdehyde/2-mercaptoethanol was performed at excitation and emission wavelengths of 345 and 450 nm, respectively. The postcolumn reaction conditions such as reaction temperature, derivatization reagent flow rate, and reagents concentration were studied due to steric hindrance of amino group of memantine. The derivatization reaction was applied for the hydrophilic interaction liquid chromatography method which was based on Cogent Silica-C stationary phase with a mobile phase consisting of a mixture of 10 mmol/L citric acid and 10 mmol/L o-phosphoric acid (pH 6.0) with acetonitrile using an isocratic composition of 2:8 v/v. The benefit of the reported approach consists in a simple sample pretreatment and a quick and sensitive hydrophilic interaction chromatography method. The developed method was validated in terms of linearity, accuracy, precision, and selectivity according to the International Conference on Harmonisation guidelines. The developed method was successfully applied for the analysis of commercial memantine tablets.

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A new simultaneous derivatization and microextration method for the determination of memantine hydrochloride in human plasma

Cited by 13 publications

References 24 publications

A review of the application of hollow-fiber liquid-phase microextraction in bioanalytical methods – A systematic approach with focus on forensic toxicology

A review of the application of hollow-fiber liquid-phase microextraction in bioanalytical methods – A systematic approach with focus on forensic toxicology

3D spongy-like Au film for highly stable solid contact potentiometric ion selective electrode: application to drug analysis

Optimization of o‐phtaldialdehyde/2‐mercaptoethanol postcolumn reaction for the hydrophilic interaction liquid chromatography determination of memantine utilizing a silica hydride stationary phase

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