2023
DOI: 10.1002/mp.16742
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A new sonoablation using acoustic droplet vaporization and focused ultrasound: A feasibility study

Hui Li,
Huan He,
Jiawei Tang
et al.

Abstract: BackgroundHistotripsy and boiling histotripsy are two methods of mechanical ablation that use high‐pressure focused ultrasound (FUS).PurposeHere, a new bubble sonoablation technique was investigated using low‐pressure FUS in combination with local injection of perfluoropentane (PFP) in rabbit liver.MethodsFifteen healthy New Zealand white rabbits were treated with FUS alone, FUS + PFP or PFP alone. FUS was performed using a single‐element focused transducer (frequency 596 kHz, 0.27 ms pulses, 0.54% duty cycle,… Show more

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