A New Supported Manganese-Based Coordination Complex as a Nano-Catalyst for the Synthesis of Indazolophthalazinetriones and Investigation of Its Antibacterial Activity

Abstract

A new magnetic supported manganese-based coordination complex (Fe3O4@SiO2@CPTMS@MBOL@ Mn) was prepared in consecutive stages and characterized via various techniques (VSM, SEM, TEM, XRD, FT-IR, EDX, TG-DTA, and ICP). To evaluate its application, it was used for synthesis of divers Indazolophthalazinetriones in a simple procedure via the one-pot three-component condensation reaction of aldehydes, dimedone, and phthalhydrazide in ethanol under reflux conditions. The Mn catalyst can be recycled without any noticeable loss in catalytic activity. Additionally, the antibacterial properties of the nano-catalyst were studied against some bacterial strains.

Silver-assisted reduction of nitroarenes by an Ag-embedded curcumin/melamine-functionalized magnetic nanocatalyst

“…4b at ca. 43° and 60° are related to the functionalization by CPTMS, but they overlap with (4 0 0) and (4 4 0) of miller indices of Fe 3 O 4 magnetic NPs 66 . The attained results in Fig.…”

“…Also, CPTMS functionalization appeared with peaks at 43° and 60°. However, these peaks and those related to the Mel linker overlapped with magnetic NPs' distinguished peaks [66][67][68] . The Ag NPs with diffraction peaks at 2θ = 38.26°, 44.47°, 64.71°, and 77.74° with 01-087-0719 reference card number have emerged in the XRD pattern 10 www.nature.com/scientificreports/ After the NB reduction completion at optimum conditions, the nanocatalyst was filtered, and the ICP test was taken from the supernatant (Figure S12).…”

The enhancing oxidation performance through a magnetic supported manganese system in low temperature

“…Shifting from 1664 to 1602 cm − 1 can be related to the interaction between manganese and nitrogen of C = N bond. Moreover, at 408.93 cm − 1 , a weak peak can be related to the Mn-N band [29].…”

“…According to Fig. 2, the diffraction peaks (Fe 3 O 4 @SiO 2 grey) at 2θ = at 10, 30, 35, 45, 53, 57, and 63 con rm the silica effectively coated on the cubic spinel crystal planes of Fe 3 O 4 (JCPDS 19-0629) [29] and peaks (Fe 3 O 4 @SiO 2 @CPTMS@MBOL@Mn green) at 2θ at 30,35,39,43,56 is related to crystalline nature of Mn catalyst (JCPDS 24-0508) [30].…”

“…The immobilization of manganese complexes on solid supports has obtained considerable attention according to the ability of adopting a wide variety of oxidation states, lower toxicity, and low price in comparison with other transition metal systems [26,27]. Commonly, organosilicon materials are necessary for the generation of heterogeneous Mn catalysts immobilized on inorganic substrates as support [28,29]. Very recently, different reports have appeared on Mn-based catalysts that are able to catalyze the oxidation of alcohols with high e ciency.…”