A new technique for hemodilution, preparation of autologous platelet-rich plasma and intraoperative blood salvage in cardiac surgery

Abstract

We have developed a new system for the production of autologous platelet-rich plasma and red blood cell concentrates to be used in autologous transfusion support of cardiac surgery patients. In 15 operations no homologous blood products were required. Costs were diminished since with the same harness it was possible to carry out the intraoperative blood salvage and concentrate the erythrocytes contained in the oxygenator and its lines. Indirect costs were also reduced since no infective complication was observed due to homologous blood products.

Effects of platelet rich plasma on fascial healing in rats with fecal peritonitis

“…PRP was used for the first time in 1987 by Ferrari et al 11 with the purpose of reducing the transfusion of homologous…”

Autologous Platelet Rich Plasma for Neck and Lower Back Pain Secondary to Spinal Disc Herniation: Midterm Results

“…It is a volume of fractionated plasma from the patient's own blood that contains platelet concentrate. Autologous PRP injections were reportedly first used in 1987 in an open-heart surgery [19]. It was also used, over 20 years ago, in the dental field for promoting accelerated wound healing in cancer patients following jaw reconstruction.…”

A randomized control study to assess the efficacy of platelet rich plasma and local corticosteroid injection in treatment of chronic plantar fasciitis

“…9 Recently, promising results were reported with the use of platelet-rich plasma (PRP) injections for treating muscle and tendon injuries and degeneration. [10][11][12][13][14][15][16] The use of autologous PRP was first used in 1987 by Ferrari, et al 17 PRP is a bioactive component of whole blood with platelet concentrations elevated above baseline and containing high levels of various growth factors. 18 The rationale for PRP benefit lies in reversing the blood ratio by decreasing red blood cells (RBC) to 5%, which are less useful in the healing process, and increasing platelets to 94% to stimulate recovery.…”