A new technique to improve the mechanical and biological performance of ultra high molecular weight polyethylene using a nylon coating

Firouzi, Dariush; Youssef, Aya; Amer, Momen; Srouji, Rami; Amleh, Asma; Foucher, Daniel A.; Bougherara, Habiba

doi:10.1016/j.jmbbm.2014.01.001

Cited by 48 publications

(19 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They are used popularly to enhance the performance of biomaterials. A range of properties can be improved including osteoinductive properties [93], hydrophilicity [94], mechanical and biological properties [95,96], surface properties (e.g., surface free energy) [97], and biotribological properties [94]. Surface coating by adding materials on the top surface will be briefly reviewed in the next paragraph.…”

Section: Surface Coatingmentioning

confidence: 99%

“…In the process, often a thin layer of a hard metallic material is added on the bulk material to improve its properties. More recently, nylon coating [95] on UHMWPE was reported to achieve lower cytotoxicity, less wear debris-induced osteolysis, and superior mechanical properties compared to neat UHMWPE. Zirconium carbon nitrides (ZrCxN1-x) coatings with embedded silver nanoparticles [94] were used as a surface modification option for multifunctional purposes including antimicrobial effect, corrosion resistance and maintaining or even improving their mechanical and tribological performance.…”

Section: Surface Coatingmentioning

confidence: 99%

See 1 more Smart Citation

Wear Performance of UHMWPE and Reinforced UHMWPE Composites in Arthroplasty Applications: A Review

2015

View full text Add to dashboard Cite

Abstract:As the gold standard material for artificial joints, ultra-high-molecular-weight polyethylene (UHMWPE) generates wear debris when the material is used in arthroplasty applications. Due to the adverse reactions of UHMWPE wear debris with surrounding tissues, the life time of UHMWPE joints is often limited to 15-20 years. To improve the wear resistance and performance of the material, various attempts have been made in the past decades. This paper reviews existing improvements made to enhance its mechanical properties and wear resistance. They include using gamma irradiation to promote the cross-linked structure and to improve the wear resistance, blending vitamin E to protect the UHMWPE, filler incorporation to improve the mechanical and wear performance, and surface texturing to improve the lubrication condition and to reduce wear. Limitations of existing work and future studies are also identified.

show abstract

Section: Surface Coatingmentioning

confidence: 99%

Section: Surface Coatingmentioning

confidence: 99%

Wear Performance of UHMWPE and Reinforced UHMWPE Composites in Arthroplasty Applications: A Review

2015

View full text Add to dashboard Cite

show abstract

“…5,[13][14][15] Most of the recent works have been focused on the designing of the coating methods, which should protect the bone tissue from periprostheticosteolysis and improve the biocompatibility of the material. Nylon coating, 16 titanium and hydroxyapatite coating, 17 and gold coating 18 showed effectiveness on the improvement of biological performance of UHMWPE. To the best of our knowledge, the studies of applying biomolecular coatings incorporating growth factors to modify UHMWPE have not been accomplished.…”

Section: Introductionmentioning

confidence: 96%

Surface modification of vascular endothelial growth factor-loaded silk fibroin to improve biological performance of ultra-high-molecular-weight polyethylene via promoting angiogenesis

Ai¹,

Sheng²,

Cai³

et al. 2017

IJN

View full text Add to dashboard Cite

Ultra-high-molecular-weight polyethylene (UHMWPE) has been applied in orthopedics, as the materials of joint prosthesis, artificial ligaments, and sutures due to its advantages such as high tensile strength, good wear resistance, and chemical stability. However, postoperative osteolysis induced by UHMWPE wear particles and poor bone–implant healing interface due to scarcity of osseointegration is a significant problem and should be solved imperatively. In order to enhance its affinity to bone tissue, vascular endothelial growth factor (VEGF) was loaded on the surface of materials, the loading was performed by silk fibroin (SF) coating to achieve a controlled-release delivery. Several techniques including field emission scanning electron microscopy (FESEM) and attenuated total reflectance (ATR)-Fourier transform infrared (FTIR) and water contact angle measurement were used to validate the effectiveness of introduction of SF/VEGF. The result of ELISA demonstrated that the release of VEGF was well maintained up to 4 weeks. The modified UHMWPE was evaluated by both in vitro and in vivo experiments. According to the results of FESEM and cell counting kit-8 (CCK-8) assay, bone marrow mesenchymal stem cells cultured on the UHMWPE coated with SF/VEGF and SF exhibited a better proliferation performance than that of the pristine UHMWPE. The model rabbit of anterior cruciate ligament reconstruction was used to observe the graft–bone healing process in vivo. The results of histological evaluation, microcomputed tomography (micro-CT) analysis, and biomechanical tests performed at 6 and 12 weeks after surgery demonstrated that graft–bone healing could be significantly improved due to the effect of VEGF on angiogenesis, which was loaded on the surface by SF coating. This study showed that the method loading VEGF on UHMWPE by SF coating played an effective role on the biological performance of UHMWPE and displayed a great potential application for anterior cruciate ligament reconstruction.

show abstract

“…Polyamide (PA), an important semi-crystalline polymer, is used in many fields, such as military equipment [1], aerospace materials [2], insulation and textile materials [3,4], due to its good mechanical, thermal and chemical properties [5,6]. The crystal structure and structural transformation play decisive roles in the properties of the materials during processing [7,8]. Some researchers have extensively explored the crystalline phase transitions during the process of heating or cooling [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

The Thermal Behavior of γ-PA1010: Evolution of Structure and Morphology in the Simultaneous Thermal Stretched Films

Zhang

Líu

et al. 2020

Materials

View full text Add to dashboard Cite

In this work, polyamide 1010 (PA1010) films were prepared by melt-quenching. A wide-angle X-ray diffractometer (WAXD) with a thermal stretching stage was used to investigate the structure transformation, crystallinity and degree of orientation in the course of simultaneous thermally stretched PA1010. The crystallinity increased along with the increase of draw ratio and then decreased as the draw ratio was over 2.00 times-which the maximum value reached when the draw ratio was about 2.00 times. The degree of orientation of γ-PA1010 was much greater at higher temperature than room temperature (RT); the difference gradually became weaker with the increase of draw ratio. There was a linear relationship between the draw ratios and tensile force at higher temperatures, and the tensile force increased with the increase of draw ratios. The tensile force may induce crystallization and promote orientation in the course of simultaneous thermally stretched PA1010. These phenomena are beneficial to understand the structure-processing-performance relationship and provide some theoretical basis for the processing and production.

show abstract

A new technique to improve the mechanical and biological performance of ultra high molecular weight polyethylene using a nylon coating

Cited by 48 publications

References 81 publications

Wear Performance of UHMWPE and Reinforced UHMWPE Composites in Arthroplasty Applications: A Review

Wear Performance of UHMWPE and Reinforced UHMWPE Composites in Arthroplasty Applications: A Review

Surface modification of vascular endothelial growth factor-loaded silk fibroin to improve biological performance of ultra-high-molecular-weight polyethylene via promoting angiogenesis

The Thermal Behavior of γ-PA1010: Evolution of Structure and Morphology in the Simultaneous Thermal Stretched Films

Contact Info

Product

Resources

About