A newly described thoracic vascular malformation in fetuses with Down syndrome

Abstract

Objectives

Prenatal ultrasound diagnosis of Down syndrome. After major malformations, soft markers, nuchal translucency and skeletal signs, a new vascular sign?

“…The intrathoracic vascular lesion reported by Prefumo and coworkers1 in this issue of the journal can be considered as the fourth vascular abnormality reported in fetuses with trisomy 21. This entity is not known from postnatal series of individuals with trisomy 21.…”

“…Down syndrome detection continues to be one of the main challenges of perinatal medicine, and its detection seems as complex as the seemingly infinite number of signs and markers that have been reported in pre‐ and postnatal series. In this issue of the journal, Prefumo et al 1 report on another possible marker, i.e. a thoracic vascular malformation.…”