Oncology, a complex multifactor etiology has eluded all-inclusive prevention and remission by a lack of comprehensive understanding of a singular causation at the most fundamental physical level. Current physiological models address the myriad branches but not the global biophysical root of aetiology. Current thinking claims that underlying quantum field dynamics are the 'basement of reality'. Einstein emphatically stated comparably to his General Relativity, that 'it was merely a convenient stopping place on the road to a more unified theory'. We propose that oncogenesis (for the several hundred tabulated cancers) occurs from one single causative factor at the root of the three considered branches of causation. Physical science (which includes chemistry, biochemistry or biophysics) has evolved from 3D Newtonian classical mechanics to the current vogue (albeit experimentally verified) of 4D quantum mechanics. Empirical access to the 3 rd regime of unified field mechanics (UFM) with inherent additional degrees of freedom is imminent. In regards to that perspective, it is proposed, that a 'telergic stressor' mediated by noetic action of the unified field produces conformal change in protein molecules that can cascade into a system of oncogenic specificity. Although the action of this fundamental stressor appears extracurricular to the current investiture on the 'branches of causation': Environmental (radiation, chemical), genetic/epigenetic, or psychosomatic; this paradigm shift is in process as threshold violations of QED (Quantum Electrodynamics) are occurring in more than one arena. The epigenome is involved in regulating gene expression, development, tissue differentiation, and suppression of transposable elements. Unlike the underlying genome which is largely static within an individual, the epigenome can be dynamically altered by external conditions. Numerous mutations occur on the pathway to the onset of a cancer; we quantify a single Unified Field noetic effect that applies to the aetiology of all cancer.Le microbe n'est rien, le terrain est tout -Pasteur.