A note About the Incidence and Origin of Hb D-Punjab in Xinjiang, People's Republic of China

Li, H J; Liu, D X; Li, L; Liu, Z G; Lo, Simon; Zhao, Junhong; Han, Xingyu; Yu, Wang

doi:10.3109/03630268609036571

Cited by 3 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The geographical distribution decreases from west to east along the Silk Road. These findings support the concept that Hb D-Punjab originated in Central Asia and not in Mongolia, as has been suggested (Li et al 1986b;Lehmann and Huntsman 1974).…”

Section: Discussionsupporting

confidence: 80%

Abnormal hemoglobins in the Silk Road region of China

Houjun¹,

Zhao

Fan³

et al. 1990

Hum Genet

View full text Add to dashboard Cite

A review is presented of the occurrence of 24 abnormal hemoglobins (13 alpha-chain variants and 11 beta-chain variants) in populations in the Silk Road area of Northwestern China. Most frequently occurring were Hb D-Punjab [beta 121(GH4)Glu----Gln] in Uygurs, Kazaks, and Khalkhas, Hb G-Taipei [beta 22(B4)Glu----Gly] in persons of the Han nationality, and Hb G-Coushatta [beta 22 (B4)Glu----Ala] in the Uygurs, Kazaks, Hans, and related nationalities. The data suggest that these variants likely originated in Central Asia, in the Han nationality of China, and in the minorities of northern China, respectively. Other variants occurred at considerably lower frequencies and were imported from other countries or arose as independent mutations. Two variants [Hb Tashikuergan or alpha 19(AB1)Ala----Glu; Hb Tianshui or beta 39(C5) Gln----Arg] were observed for the first time. The data from this study of the many variants support the movements of various populations in this area, as reported in numerous historical documents.

show abstract

Section: Discussionsupporting

confidence: 80%

Abnormal hemoglobins in the Silk Road region of China

Houjun¹,

Zhao

Fan³

et al. 1990

Hum Genet

View full text Add to dashboard Cite

show abstract

“…In traditional Chinese medicine, A. rupestris aerial parts are used for detoxification and for protecting the liver [8]. Moreover, many pharmacological activities of A .…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, many pharmacological activities of A . rupestris were demonstrated such as anti-tumor, antioxidant, antibacterial, and antivirus properties [8]. It thus seems that this medicinal herb is quite safe for human consumption because it has been used as a medicinal herb for hundreds of years.…”

Section: Resultsmentioning

confidence: 99%

“…rupestris ) is a perennial subshrub distributed in dry hills, desert or semi-desert steppes as well as dry river valleys (1,100–2,900 m) in the Xinjiang Uyghur Autonomous Region of China and also distributed in Afghanistan, Kazakhstan, Kyrgyzstan, Mongolia, Russia, Tajikistan; East and North of Europe [7]. A. rupestris is a well-known traditional Chinese medicinal plant in the Xinjiang of China used for detoxification, with antitumor, antibacterial, and antivirus properties, and is used as well for protecting the liver [8]. Several alkaloids, sesquiterpenoids, sesquiterpene lactone glycosides, triterpenoids, and flavonoids have been identified from A. rupestris [9,10,11,12,13,14,15,16,17].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Identification of Repellent and Insecticidal Constituents of the Essential Oil of Artemisia rupestris L. Aerial Parts against Liposcelis bostrychophila Badonnel

Liu

et al. 2013

Molecules

View full text Add to dashboard Cite

Abstract:The aim of this research was to determine the chemical composition and insecticidal and repellent activity of the essential oil of Artemisia rupestris L. aerial parts against the booklice Liposcelis bostrychophila Badonnel and isolation of insecticidal and repellent constituents from the essential oil. The essential oil of A. rupestris was obtained by hydrodistillation and analyzed by GC-MS. A total of 30 components of the essential oil of A. rupestris was identified and the principal compounds in the essential oil were α-terpinyl acetate (37.18%), spathulenol (10.65%), α-terpineol (10.09%), and linalool (7.56%), followed by 4-terpineol (3.92%) and patchoulol (3.05%). Based on bioactivity-guided fractionation, the four active constituents were isolated from the essential oil and identified as α-terpineol, α-terpinyl acetate, 4-terpineol and linalool. The essential oil of A. rupestris exhibited contact toxicity against L. bostrychophila with LD 50 value of 414.48 µg/cm ). The essential oil of A. rupestris (LC 50 = 6.67 mg/L air) also possessed fumigant toxicity against L. bostrychophila while the four constituents, 4-terpineol, α-terpineol, α-terpinyl acetate and linalool had LC 50 values of 0.34, 1.12, 1.26 and 1.96 mg/L air, respectively. α-Terpinol and α-terpinyl acetate showed strong repellency against L. bostrychophila, while linalool and 4-terpinol exhibited weak repellency. The results indicate that the essential oil of A. rupestris aerial parts and its constituent compounds have potential for development into natural insecticides or fumigants as well as repellents for control of insects in stored grains.

show abstract