A novel approach to design intraocular lenses with extended depth of focus in a pseudophakic eye model

Rao, Feng; Wang, Zhaoqi; Liu, Yong-Ji; Wang, Yan

doi:10.1016/j.ijleo.2010.06.035

Cited by 5 publications

(2 citation statements)

References 12 publications

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“…Ray-tracing eye models are useful to evaluate the IOL design and power calculation [ 17 – 27 ]. The use of an individual eye model based on personal eye parameters best represents the optics of real eyes and is useful to obtain the design and evaluation of IOLs optical performance [ 17 , 25 , 28 , 29 ]. The main purpose of this paper is to introduce the use of individual ray-tracing eye models to investigate whether the variety of un-measured and unpredictable pseudo-phakic parameters would eliminate the retinal image benefit of having aspheric and individually customized IOL designs based on the corneal topography and eye length.…”

Section: Introductionmentioning

confidence: 99%

Comparison of retinal image quality with spherical and customized aspheric intraocular lenses

Guo

Goncharov

Dainty

2012

Biomed. Opt. Express

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We hypothesize that an intraocular lens (IOL) with higher-order aspheric surfaces customized for an individual eye provides improved retinal image quality, despite the misalignments that accompany cataract surgery. To test this hypothesis, ray-tracing eye models were used to investigate 10 designs of mono-focal single lens IOLs with rotationally symmetric spherical, aspheric, and customized surfaces. Retinal image quality of pseudo-phakic eyes using these IOLs together with individual variations in ocular and IOL parameters, are evaluated using a Monte Carlo analysis. We conclude that customized lenses should give improved retinal image quality despite the random errors resulting from IOL insertion.

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Section: Introductionmentioning

confidence: 99%

Comparison of retinal image quality with spherical and customized aspheric intraocular lenses

Guo

Goncharov

Dainty

2012

Biomed. Opt. Express

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“…Therefore, personalized modeling of the lens adjustment process for specific groups is crucial. Personalized lens modeling can not only improve the accuracy of disease diagnosis and surgical simulation but also help guide the design of intraocular lens (iOL) structure, so that it can not only correct defocus and astigmatism but also correct spherical aberrations, thereby improving the visual function of the human eye [27][28][29]. At present, personalized modeling technology has achieved remarkable research results in the pulmonary artery, liver pipeline, and artificial bone [30][31][32].…”

Section: Introductionmentioning

confidence: 99%

Establishment of Personalized Finite Element Model of Crystalline Lens Based on Sweep-Source Optical Coherence Tomography

Liu

Li²,

Liu

et al. 2022

Photonics

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The virtual lens model has important value in ophthalmic research, clinical diagnosis, and treatment. However, the establishment of personalized lens models and the verification of accommodation accuracy have not been paid much attention. We proposed a personalized lens model establishment and the accommodation accuracy evaluation method based on sweep-source optical coherence tomography (SS-OCT). Firstly, SS-OCT is used to obtain a single lens image in the maximum accommodation state. After refraction correction, boundary detection, and curve fitting, the central curvature radius, thickness, and lens nucleus contour of the anterior and posterior surfaces of the lens were obtained. Secondly, a personalized finite element model improved from Burd’s model was established using these individual parameters, and the adaptation process of the lens model was simulated by pulling the suspensory ligament. Finally, the shape and refractive power changes of the real human lens under different accommodation stimuli were collected and compared with the accommodation process of the finite element model. The results show that the accommodation process of the finite element model is highly consistent with that of the real lens. From the un-accommodation state to the maximum-accommodation state, the difference rate of all geometric and refractive parameters between the two is less than 5%. Thus, the personalized lens finite element model obtained by the calibration and correction of the existing model can accurately simulate the regulation process of a specific human lens. This work helps to provide a valuable theoretical basis and research ideas for the study of clinical diagnosis and treatment of related diseases.

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Effects of photopic and cirtopic illumination on steady state pupil sizes

Rao

Chan

2017

Vision Research

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The conventional view was that cones are responsible for pupil constriction in photopic lighting conditions. With the discovery of intrinsically photosensitive retinal ganglion cells (ipRGC), it was found that signals from ipRGCs along with cones mediated the pupil light reflex in photopic lighting conditions. Although both signals contributed, it was unclear how these signals were summed. In the work reported here, steady-state pupil size was measured with an infrared camera under LED lighting conditions with different color temperatures and luminance. A formula was then derived for pupil size according to the linear summation of cirtopic and photopic luminance. This formula allowed direct calculations to predict pupil size well when LED photopic luminance ranged from about 50cd/m to 300cd/m, which is the general luminance level range for computer and smartphone screens.

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A novel approach to design intraocular lenses with extended depth of focus in a pseudophakic eye model

Cited by 5 publications

References 12 publications

Comparison of retinal image quality with spherical and customized aspheric intraocular lenses

Comparison of retinal image quality with spherical and customized aspheric intraocular lenses

Establishment of Personalized Finite Element Model of Crystalline Lens Based on Sweep-Source Optical Coherence Tomography

Effects of photopic and cirtopic illumination on steady state pupil sizes

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