A Novel Cd(II) Isophthalate Complex with Triethanolamine: Crystal Structure, Fluorescence and Antimicrobial Activity

Abstract

A mixed ligand Cd(II) complex [Cd(IsoPht)(TEA)H2O]·3H2O was synthesized for the first time by using isophthalic acid (H2IsoPht) and tetradentate triethanolamine (TEA) and characterized by X-ray single-crystal diffraction, FT-IR, and thermogravimetric analysis (TGA). This novel complex crystallizes in the triclinic system with P-1 space group and distorted monocapped trigonal prismatic geometry. The Cd(II) has seven coordinates with bidentate IsoPht, a TEA in the tetradentate mode, and an aqua ligand. The fluorescence properties of the Cd(II) complex and TEA ligand were investigated at room temperature. The present Cd(II) complex was also tested for its antimicrobial activity by in vitro agar diffusion method against some Gram-positive and Gram-negative bacteria and a fungus.

Computational studies, antimicrobial activity, inhibition of biofilm production, and safety profile of the cadmium complex of 1,10‐phenanthroline and cyanoguanidine

“…Moreover, the [Cd(1‐[[3‐methyl‐pyridine‐2‐ylimino]‐methyl]‐naphthalen‐2‐ol)Cl] complex showed significant antioxidant activity against DPPH (IC 50 = 138 μg ml −1 ) and antibacterial properties (judged by the diameters of inhibition zones), 20 like the cadmium (II) complex with reduced Schiff bases derived from N , N ′‐ o ‐phenylenebis (salicylideneimine) 21 . Other reports of cadmium based compounds proposed antibacterial and antifungal properties employing preliminary screening techniques based on Kirby‐Bauer's method 22–27 . Few reports of antibiofilm activity of cadmium complexes are available in the literature.…”

“…21 Other reports of cadmium based compounds proposed antibacterial and antifungal properties employing preliminary screening techniques based on Kirby-Bauer's method. [22][23][24][25][26][27] Few reports of antibiofilm activity of cadmium complexes are available in the literature. Likewise, two tetranuclear Cd (II) complexes with salen-type Schiff base ligands showed antibiofilm activity against Enterococcus gallinarum MTCC7049 and Proteus vulgaris MTCC744, 15 whereas the [Cd (sulfamethoxazolate) 2 ] complex showed greater biofilm inhibition (and destruction of already formed biofilm) than the free antibiotic against Mycobacterium fortuitum and Mycobacterium abscessus.…”