A novel colorimetric/fluorometric dual-channel sensor based on phenolphthalein and Bodipy for Sn (II) and Al (III) ions in half-aqueous medium and its applications in bioimaging

Photophysical Challenges and Antenna Effect Between Click Reaction-based Bodipy Derivatives Manufactured From Knorr Pyrrole

“…For this reason, researchers have synthesized a lot of Bodipy derivatives with several reaction techniques like click chemistry to obtain a shift in emission and absorption wavelengths [10][11][12]. Bodipy uorophores, which can be used in the detection of metal ions by making use of changes in uorescence wavelength and intensity, just as in porphyrins and phthalocyanines, are increasingly signi cant for bio-imaging applications and cytotoxicity [13][14][15][16]. Moreover, Bodipy uorophores undertake to the tasks of photodynamic therapy studies, which the principle that the photo-stimulant creates cytotoxic singlet oxygen around it after absorbing light in the near-infrared region [17][18][19][20].…”

Simple Colorimetric and Fluorescence Chemosensing Probe for Selective Detection of Sn2+ Ions in an Aqueous Solution: Evaluation of the Novel Sensing Mechanism and Its Bioimaging Applications

“…1−3 In the human body, small concentrations of inorganic cations take part in significant biological, chemical, and enzymatic activities at the cellular level. 4,5 However, excess consumption of these metal ions may lead to numerous neural disorders such as Wilson's disease, Alzheimer's disease, and Menkes syndrome. 6,7 Among the various transition metals, tin (Sn) is an important element in human health.…”

“…33 Recently, Gul et al described the synthesis of phenolphthalein and BODIPY-based colorimetric/ fluorescence dual-channel sensors for Sn 2+ and Al 3+ recognition and evaluated their bioimaging applications. 4 Most of these reported chemosensing probes have several practical disadvantages such as interference of coexisting metal ions, poor performance in aqueous solutions, poor selectivity, weak emission properties, and diminished biocompatibility which means that they induce the toxicity or immune response upon residing in the human/animal living cells. Thus, in the treatment of medical implants to the humans, the biocompatibility of the material is very important to avoid the denial of implantation by the body cells and tissues.…”

“…Industrialization has resulted in the release of a large amount of heavy metals into the environment, seriously threatening human life. − In the human body, small concentrations of inorganic cations take part in significant biological, chemical, and enzymatic activities at the cellular level. , However, excess consumption of these metal ions may lead to numerous neural disorders such as Wilson’s disease, Alzheimer’s disease, and Menkes syndrome. , Among the various transition metals, tin (Sn) is an important element in human health . At trace levels, Sn­(II) could help in the development of body muscles and act as an effective catalyst in the synthesis of nucleic acids and proteins.…”

“…Gao et al described the synthesis of chiral carbon dot-based nanosensors for Sn 2+ and lysine enantiomer recognition . Recently, Gul et al described the synthesis of phenolphthalein and BODIPY-based colorimetric/fluorescence dual-channel sensors for Sn 2+ and Al 3+ recognition and evaluated their bioimaging applications . Most of these reported chemosensing probes have several practical disadvantages such as interference of coexisting metal ions, poor performance in aqueous solutions, poor selectivity, weak emission properties, and diminished biocompatibility which means that they induce the toxicity or immune response upon residing in the human/animal living cells.…”