2024
DOI: 10.1016/j.talanta.2023.125434
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A novel device for the determination of liposome/water partition coefficients

Radek Jerga,
Veronika Brablecová,
Veronika Talášková
et al.
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“…The oil/water partition coefficient (Lg P) is commonly used to quantify lipophilicity in the biomedical fields, and here n -octanol and PBS solution are chosen as the solvents. The shake flask method is employed to test the Lg P of G-CDs. Figure f shows that only the upper n -octanol layer is luminescent under UV light, verifying G-CDs are lipophilic. According to the absorbance values of the upper and lower layers as well as standard curves, the retention concentrations of G-CDs in the two layers after sufficient distribution are calculated to be 13.209 and 0.090 μg·mL –1 , respectively (Figure g and h).…”
mentioning
confidence: 99%
“…The oil/water partition coefficient (Lg P) is commonly used to quantify lipophilicity in the biomedical fields, and here n -octanol and PBS solution are chosen as the solvents. The shake flask method is employed to test the Lg P of G-CDs. Figure f shows that only the upper n -octanol layer is luminescent under UV light, verifying G-CDs are lipophilic. According to the absorbance values of the upper and lower layers as well as standard curves, the retention concentrations of G-CDs in the two layers after sufficient distribution are calculated to be 13.209 and 0.090 μg·mL –1 , respectively (Figure g and h).…”
mentioning
confidence: 99%