A Novel Diagnostic Tool for Detecting Functional Patency of the Small Bowel: the Given Patency Capsule

Abstract

This feasibility study has shown that the Given patency capsule is a safe, effective, and convenient tool for assessment of functional patency of the small bowel. It can indicate functional patency even in cases where traditional radiology indicates stricture.

Patency© and agile© capsules

“…A prospective, multi-center trial was designed to assess the clinical usefulness and safety of the PC capsule in patients with intestinal strictures suspected from clinical and/or radiological data. The global data of this trial have not been published, but the results of four of these centers have been reported (Table 1) [24][25][26][27] . In the series reported by Spada et al [24] , 30 out of 34 (88.2%) patients with known or suspected small bowel stricture retrieved the capsule in the stool.…”

“…The global data of this trial have not been published, but the results of four of these centers have been reported (Table 1) [24][25][26][27] . In the series reported by Spada et al [24] , 30 out of 34 (88.2%) patients with known or suspected small bowel stricture retrieved the capsule in the stool. After the excretion, the PC was intact in 20 cases (median transit time 22 h), and disintegrated in 10 patients (median transit time 53 h).…”

The Diagnostic Effect of Capsule Endoscopy in 31 Cases with Subacute Small Bowel Obstruction

“…The patency capsule [11] is composed of lactose, remains intact in the gastrointestinal tract for 40-100 h post-ingestion, and disintegrates thereafter. Spada et al [12] have reported that 94% (30/34) of cases with small bowel stricture passed the intact or disintegrated capsule in the stools. Expulsion was confirmed in three cases by fluoroscopy, and the remaining patient withdrew consent to the study.…”

Review: Diagnosis and management of mid-gastrointestinal bleeding by double-balloon endoscopy

“…The patency capsule (PC) is a new nonendoscopic dissolvable capsule to check the patency of the digestive tract in a noninvasive manner. PC seems to be a useful noninvasive tool to identify which patients with suspected strictures could safely ingest the standard CE Banerjee et al 2007;Spada et al 2007;Signorelli et al 2006;Spada et al 2005].…”