A novel electrochemical imprinted sensor for ultrasensitive detection of the new psychoactive substance “Mephedrone”

Razavipanah, Iman; Alipour, Esmaeel; Deiminiat, Behjat; Rounaghi, Gholam Hossein

doi:10.1016/j.bios.2018.08.016

Cited by 49 publications

(31 citation statements)

References 49 publications

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“…These electrodes were also used for mephedrone analysis [43,44]. Mephedrone had already been detected using electrochemical methods [43][44][45][46][47][48][49].…”

Section: Introductionmentioning

confidence: 99%

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

Papaioannou

Karastogianni

Girousi

2022

Sensors

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Mephedrone, also known as 4-methylmethcathinone, is growing into a prominent recreational drug for young people. When it came to detecting mephedrone, limited efforts were made using electrochemical sensors. As a result, this application depicts the fabrication of a new, sensitive, selective, and economical electrochemical sensor capable of detecting mephedrone by using silver nanoparticles capped with saffron produced through electropolymerization to modify carbon paste electrodes (CPEs). Silver nanoparticles (AgNPs) were capped with saffron (AgNPs@Sa) using a green method. AgNPs@Sa were studied using electron scanning microscopy (SEM) and UV-vis spectroscopy. The sensor was evaluated under the optimum condition to determine its analytical features. The results showed that this procedure had a wide linear range, low detection limit and sufficient reproducibility. Furthermore, the sensor posed sufficient stability. Moreover, it was applied in the determination of mephedrone in urine samples, showing the potential applicability of this electrochemical sensor in real sample analysis.

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“…These electrodes were also used for mephedrone analysis [43,44]. Mephedrone had already been detected using electrochemical methods [43][44][45][46][47][48][49].…”

Section: Introductionmentioning

confidence: 99%

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

Papaioannou

Karastogianni

Girousi

2022

Sensors

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“…So, the higher RLS intensity observed for nanocomposite in the presence of famotidine is due to the bigger molecular volume after assembling of famotidine on the nanoparticle's surface. 40 for determination of epinephrine in serum by using graphene quantum dots -chitosan (GQD-CS) modified CPE electrode, 41 for determination of nifedipine and dehydronifedipine by using MWCNT modified glassy carbon electrode (GCE), 42 for determination of epirubicin in spiked serum samples by using both 3D Fe 3 O 4 decorated single wall carbon nanotubes (Fe 3 O 4 -SWCNTs) nanocomposite and 1-methyl-3-octylimidazlium chloride (MOCTICl) as amplifier into CPE, 43 for determination of didanosine in spiked serum samples by using pencil graphite electrode modified with polypyrrole and reduced graphene oxide (PGE/PPy/rGO), 44 for determination of midazolam in spiked urine samples by using MIP nanoparticles modified CPE, 45 for determination of trimipramine in spiked urine and serum samples by using CPE modified with MWCNTs and a nano-structured MIP, 46 for determination of mephedrone in spiked urine and plasma samples by using MIP/polytyramine/f-MWCNT@ AuNPs nanocomposite/GCE, 47 for determination of tramadol by using CPE modified with nanographene/ tramadol-MIP/ionic liquid (GNS@Ag NPs/ MIPNPs/ [BMP]Tf2N RTIL) with measured concentration between 45.2 -51.0 µmol L -1 in urine sample of patients receiving tramadol, 48 for determination of dopamine in spiked serum samples by using a MWCNT/ionic liquid paste electrode / tetra-n-octylammonium triiodide (MWCNT/ TOAI 3 /CIL), 49 for determination of methimazole in serum samples by using CuNPs-P-L-Argenine/MWCNTs/GCE, 50 for determination of meloxicam in the spiked plasma samples by using CPE modified with gold nanoparticles modified choline chloride functionalized graphene oxide (AuNPs-ChCl-GO), 51 for detection of celecoxib in the spiked plasma samples by using CPE modified with AgNPs modified ChCl-GO, 52 for determination of acyclovir in spiked serum and urine samples by using GCE modified with a polymeric chitosan film decorated with MWCNTs + TiO 2 NPs, 53 for determination of isoxsuprine in spiked serum samples by using GCE modified with MWCNTs decorated with Ag NPs, 54 for determination of theophylline in spiked urine samples by using GQD modified SPE, 55 for determination of methyldopa in spiked urine samples by using a GCE modified with Cu/TiO 2 nanocomposite, 56 for simultaneous determination of epinephrine, paracetamol and tryptophan in spiked urine and serum samples by using modified CPE with Ni-doped Lewatit FO36 nano ion exchange resin, 57 for determination of favoxate hydrochloride and tolterodine tartrate in spiked urine samples by using ferrocene modified carbon paste electrode (FMCPE),…”

Section: Resonance Light Scattering Methodsmentioning

confidence: 99%

A Comprehensive Review on Developed Pharmaceutical Analysis Methods by Iranian Analysts in 2018

2020

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This article summarizes the publishing activities including bioanalytical and pharmaceutical analyses researches carried out in Iran in 2018 in order to connect academic researchers to those in industry, medical care units and hospitals. A wide spectrum of analytical methods has been used to determine and/or evaluate drug levels in the biological samples, based on physical, chemical and biochemical principles. We have compiled a concise survey of the literature covering 125 reports and tabulated the relevant analytical parameters. Chromatographic and electrochemical methods were found to be the technique of choice for many workers and almost 83% studies were performed by using these methods. This is the first annual review of the literature searching in SCOPUS database for published bioanalytical and pharmaceutical analysis researches in Iran.

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“…In addition, availability of portable, miniaturization, automation and affordable instruments with higher performance characteristics together with reasonable limits of detection and acceptable selectivity successfully cope with the demands for the determination of illicit substances in the black drug market. Notwithstanding the wide applications of electrochemical sensors for the determination of illicit substances [18][19][20][21][22], little has been reported about the determination of new psychoactive substances [22][23][24]. Moreover, it is of importance to mention that no chemical sensors have been performed yet for the determination of mCPP.…”

Section: N Hn CLmentioning

confidence: 99%

Potentiometric Signal Transduction for Selective Determination of 1-(3-Chlorophenyl)piperazine “Legal Ecstasy” Through Biomimetic Interaction Mechanism

El-Naby

2019

Chemosensors

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1-(3-chlorophenyl)piperazine (mCPP) is a wide spread new psychoactive substance produces stimulant and hallucinogenic effects similar to those sought from ecstasy. Hence, in the recent years, mCPP has been introduced by the organized crime through the darknet as a part of the illicit ecstasy market with a variable complex profile of pharmacologically active substances that pose problematic risk patterns among people who take these seized products. Accordingly, the design of selective sensors for the determination of mCPP is a very important demand. In this respect, a supramolecular architecture; [Na(15-crown-5)][BPh4] from the assembly of 15-crown-5 and sodium tetraphenylboron has been utilized as an ionophore, for the first time in the selective recognition of mCPP in conjunction with potassium tetrakis(p-chlorophenyl)borate and dioctylphthalate through polymeric membrane ion sensors. The ionophore exhibited a strong binding affinity that resulted in a high sensitivity with a slope closed to the ideal Nernstian value; 58.9 ± 0.43 mV/decade, a larger dynamic range from 10−6 to 10−2 M, a lower limit of detection down to 5.0 × 10−7 M and a fast response time of 5 s. Very important also is it was afforded excellent selectivity towards mCPP over psychoactive substances of major concern, providing a potentially useful system for the determination of mCPP in the illicit market. On comparison with the natural β-cyclodextrin as an ionophore, it exhibited more sensitivity and selectivity estimated to be the superior.

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A novel electrochemical imprinted sensor for ultrasensitive detection of the new psychoactive substance “Mephedrone”

Cited by 49 publications

References 49 publications

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

Development of an Electrochemical Sensor Using a Modified Carbon Paste Electrode with Silver Nanoparticles Capped with Saffron for Monitoring Mephedrone

A Comprehensive Review on Developed Pharmaceutical Analysis Methods by Iranian Analysts in 2018

Potentiometric Signal Transduction for Selective Determination of 1-(3-Chlorophenyl)piperazine “Legal Ecstasy” Through Biomimetic Interaction Mechanism

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