A novel fluorescent probe based on naphthimide for H2S identification and application

Zhang, Chenglu; Liu, Chang; Ye, Ding; Wang, Haitao; Nie, Shi-ru; Zhang, Yanpeng

doi:10.1016/j.ab.2023.115232

Cited by 4 publications

(1 citation statement)

References 44 publications

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“…mated to be 0.61 µM. Compared with the early results (as shown in Table S1), the LOD value is consistent with the reports by Lu and Jose [26][27][28] and good compared with the reports by Zhang [29,30]. Additionally, the pH-dependent responses of probe HND and HND to H2S were carried out.…”

Section: H 2 S Response By Probe Hndsupporting

confidence: 87%

An Aggregation-Induced Fluorescence Probe for Detection H2S and Its Application in Cell Imaging

Tang,

Zhang,

Wang

et al. 2024

Molecules

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Monitoring hydrogen sulfide (H2S) in living organisms is very important because H2S acts as a regulator in many physiological and pathological processes. Upregulation of endogenous H2S concentration has been shown to be closely related to the occurrence and development of tumors, atherosclerosis, neurodegenerative diseases and diabetes. Herin, a novel fluorescent probe HND with aggregation-induced emission was designed. Impressively, HND exhibited a high selectivity, fast response (1 min) and low detection limit (0.61 μM) for H2S in PBS buffer (10 mM, pH = 7.42). Moreover, the reaction mechanism between HND and H2S was conducted by Job’s plot, HR-MS, and DFT. In particular, HND was successfully employed to detect H2S in HeLa cells.

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