A novel fluorescent probe for hydrazine based on acetyl-deprotection and iminocoumarin formation

Xu, Wenjun; Li, Xue; Yin, Jiwei; Han, Mengnan; Liu, Weiyan; Yang, Yutao; Li, Wei

doi:10.1016/j.jphotochem.2019.112262

Cited by 14 publications

(2 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Small molecule-based probes can detect hydrazine due to the toxin's nucleophilic behavior by reacting with it to produce a visual change in colour making them potentially more costeffective and user-friendly. 6,[22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] While uorescence-based methods have the advantage of being highly sensitive, an optical response based on a simple change in the colour of a material can be more suitable for 'naked-eye' detection. A method that combines both optical techniques would provide a heightened level of reliability.…”

Section: Introductionmentioning

confidence: 99%

A dual-mode visual detector for toxic hydrazine

2021

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

A dual-mode visual detector for toxic hydrazine

2021

View full text Add to dashboard Cite

show abstract

“…By contrast, the fluorescence method [12][13][14] has become more popular in the detection of environmental pollutants due to its low cost, high sensitivity, convenient operation, and suitability for on-site detection. Although the first hydrazine fluorescent probe had been reported in 2011 [15], it was only after 2016 that efficient design strategies for hydrazine sensors appeared [16][17][18][19][20]. These design methodologies were refined after that.…”

mentioning

confidence: 99%

Fluorescence detection of hydrazine in an aqueous environment by a corrole derivative

Lu,

Yu,

Duan

et al. 2023

Luminescence

View full text Add to dashboard Cite

Broadly industrial applications of hydrazine cause environment pollution and damage to living organisms because of the highly toxicity of hydrazine. Therefore, monitoring hydrazine in environmental system is of great significance to human health. Herein, a new fluorescent probe PC‐N2H4 based on the corrole dye has been developed for the detection of hydrazine with excellent specificity, low limit of detection (LOD: 88 nM), and wide pH range (6‐12). Upon addition of hydrazine into the probe solution, the strong red fluorescence was “turned on” centered at 653 nm with a 127‐fold fluorescence intensity enhancement. The detection mechanism was proved by ESI‐MS, 1H NMR and DFT calculations. Importantly, the probe was utilized to fabricate a ready‐to‐use test strip to realize the visual inspection of hydrazine. Furthermore, PC‐N2H4 was successfully applied for practical detection of hydrazine in water samples with satisfactory recoveries ranging from 96.2% to 105.0%, indicating that the designed PC‐N2H4 is highly promising for hydrazine detection in an aqueous environment. In consideration of the diverse toxicological functions of hydrazine, PC‐N2H4 was also successfully used for imaging of exogenous hydrazine in HeLa cells and zebrafish.

show abstract

A Dual Spectroscopic Probe Based on Benzothiazole for Detection of Hydrazine

Zhang

Zhu

et al. 2021

ChemistrySelect

View full text Add to dashboard Cite

Hydrazine is widely used in fuels, fuel cell reactors and the synthesis of polymer, drug and pesticide intermediates. However, it can be contained in food and drinking water and enter organisms through the food chains because of its good water solubility, causing serious health problems. Therefore, there is an urgent need to develop new analytical reagents to detect hydrazine with high selectivity and sensitivity. In this paper, a spectroscopic probe (probe 1) for hydrazine hydrate based on the addition‐cyclization mechanism with high selectivity and sensitivity was developed. This probe can simultaneously detect hydrazine by UV‐visible and fluorescence spectra, and the corresponding detection limits are 51.7 μM and 6.7 nM, respectively. Importantly, the spectroscopic probe was successfully applied to hydrazine detection in water samples and living cells. The test strips based on the probe was also prepared for the point‐of‐care testing of hydrazine in the actual water samples.

show abstract

A novel fluorescent probe for hydrazine based on acetyl-deprotection and iminocoumarin formation

Cited by 14 publications

References 36 publications

A dual-mode visual detector for toxic hydrazine

A dual-mode visual detector for toxic hydrazine

Fluorescence detection of hydrazine in an aqueous environment by a corrole derivative

A Dual Spectroscopic Probe Based on Benzothiazole for Detection of Hydrazine

Contact Info

Product

Resources

About