2023
DOI: 10.1016/j.talanta.2023.124567
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A novel GSH-activable theranostic probe containing kinase inhibitor for synergistic treatment and selective imaging of tumor cells

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Cited by 6 publications
(2 citation statements)
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“…The stock solutions of the analytes were obtained according to the previous reports. 42,43 The stock solution of JSS-1 (50 μL) was added into a 10 mL volumetric flask and filled with mixed buffer solution (EtOH/PBS, 5/5, V/V, pH 7.4) to volume. Various concentrations of HSO 3 − /SO 3 2− or other species were added into the flask, and the variation of the fluorescence spectra was recorded.…”
Section: Methodsmentioning
confidence: 99%
“…The stock solutions of the analytes were obtained according to the previous reports. 42,43 The stock solution of JSS-1 (50 μL) was added into a 10 mL volumetric flask and filled with mixed buffer solution (EtOH/PBS, 5/5, V/V, pH 7.4) to volume. Various concentrations of HSO 3 − /SO 3 2− or other species were added into the flask, and the variation of the fluorescence spectra was recorded.…”
Section: Methodsmentioning
confidence: 99%
“…In addition to its applications in medicinal chemistry, the sulfonyl group also plays a critical role in creating various luminescent platforms, such as Texas Red-X and Rhodamine Red-X. 7 A few other examples include squaraine-sulfonamide derivatives for NIR imaging, 8 the 1,8-naphthalimide-4-sulfonamide-linked kinase inhibitor crizotinib for the interaction with GSH, 9 tracking glutathione levels within lysosomes, 10 hypoxia imaging by covalently linking fluorophores with carbonic anhydrase inhibitors, 11 sulfonamidyl luciferins, 12 multicolor fluorescent ESIPT fluorophores, 13 rhodamine derivatives for super-resolution imaging, 14 Golgi-targeting, 15,16 profiling active-EGFR in tumors, 16 locating GPR120 receptors, 17 endoplasmic reticulum (ER)-targeting pendants 18–22 and imaging the lipid droplets using mono dansylpentane (MDH). 23 In all these cases, the sulfonyl group exists as sulphonamide (R–S(O) 2 –NH 2 ), where the NH hydrogen links functional elements of interest.…”
Section: Introductionmentioning
confidence: 99%