A novel identified circ-ANKHD1 targets the miR-27a-3p/SFRP1 signaling pathway and modulates the apoptosis of granulosa cells

Li, Xiaoyan; Gao, Fenglei; Fan, Yushan; Xie, Shefeng; Li, Chengde; Li, Meng; Li, Li; Zhang, Shouquan; Wei, Hengxi

doi:10.1007/s11356-021-14699-4

Cited by 10 publications

(4 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…circRNA-010383 has been demonstrated to act as a ceRNA, reducing the expression of miR-1335a and contributing to renal fibrosis in diabetic nephropathy ( Peng et al, 2021 ). Another study by Li et al revealed that circ-ANKHD1, which targets the miR-27a-3p/SFRP1 axis, serves as a sponge for miRNAs and modulates the apoptosis of GCs ( Li et al, 2021b ). Additionally, circINHA and circSLC41A1 were found to separately inhibit porcine GC apoptosis through the miR-10a-5p/CTGF axis and the miR-9820-5p/SRSF1 axis, respectively ( Guo et al, 2019 ; Wang et al, 2022a ).…”

Section: Introductionmentioning

confidence: 99%

CircRAB11A act as miR-24-5p sponge promotes proliferation and resists apoptosis of chicken granulosa cell via EGFR/ERK1/2 and RAB11A/ PI3K/AKT pathways

Wei,

Li,

et al. 2024

Poultry Science

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

CircRAB11A act as miR-24-5p sponge promotes proliferation and resists apoptosis of chicken granulosa cell via EGFR/ERK1/2 and RAB11A/ PI3K/AKT pathways

Wei,

Li,

et al. 2024

Poultry Science

View full text Add to dashboard Cite

“…The pituitary gland plays an essential role in regulating reproductive performance, and this regulation involves coding and noncoding RNAs. Studies on the effects of long noncoding and circular RNAs on reproductive performance have focused on the ovaries ( Miao et al, 2017 ; Liu et al, 2021 ; Zhang et al, 2022 ) and granulosa cells ( Li et al, 2018 ; Li X. et al, 2021 ; Zhao et al, 2023 ), and research on their effects on reproductive performance in the pituitary gland is limited ( Yang et al, 2020 ). Long noncoding RNA (lncRNA) is transcribed by RNA polymerase II/III and is a type of RNA molecule whose length exceeds 200 bp.…”

Section: Introductionmentioning

confidence: 99%

Transcriptome analysis reveals pituitary lncRNA, circRNA and mRNA affecting fertility in high- and low-yielding goats

Mao,

Dong,

Hou

et al. 2023

Front. Genet.

View full text Add to dashboard Cite

The pituitary gland serves as the central endocrine regulator of growth, reproduction, and metabolism and plays a crucial role in the reproductive process of female animals. Transcriptome analysis was conducted using pituitary gland samples from Leizhou goats with varying levels of fecundity to investigate the effects of long noncoding RNA (lncRNA), circular RNA (circRNA), and mRNA regulation on pituitary hormone secretion and its association with goat fecundity. The analysis aimed to identify lncRNAs, circRNAs, and mRNAs that influence the fertility of Leizhou goats. GO and KEGG enrichment analyses were performed on differentially expressed lncRNAs, circRNAs, and mRNAs and revealed considerable enrichment in pathways, such as regulation of hormone secretion, germ cell development, and gonadotropin-releasing hormone secretion. The pituitary lncRNAs (ENSCHIT00000010293, ENSCHIT00000010304, ENSCHIT00000010306, ENSCHIT00000010290, ENSCHIT00000010298, ENSCHIT00000006769, ENSCHIT00000006767, ENSCHIT00000006921, and ENSCHIT00000001330) and circRNAs (chicirc_029285, chicirc_026618, chicirc_129655, chicirc_018248, chicirc_122554, chicirc_087101, and chicirc_078945) identified as differentially expressed regulated hormone secretion in the pituitary through their respective host genes. Additionally, differential mRNAs (GABBR2, SYCP1, HNF4A, CBLN1, and CDKN1A) influenced goat fecundity by affecting hormone secretion in the pituitary gland. These findings contribute to the understanding of the molecular mechanisms underlying pituitary regulation of fecundity in Leizhou goats.

show abstract

“…Circular RNAs (circRNAs) are a major type of non-coding regulatory RNAs that are produced by non-canonical back-splicing events ( Li et al, 2019a ; Liu et al, 2020 ; Ma et al, 2020 ; Li et al, 2021a ; Li et al, 2021b ). CircRNAs are known to modulate gene expression principally via sponging microRNAs (miRNAs) ( Li et al, 2020c ; Pan et al, 2020 ; Ni et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Circular RNAs in Intervertebral Disc Degeneration: An Updated Review

Sun

et al. 2022

Front. Mol. Biosci.

View full text Add to dashboard Cite

Low back pain, a common medical condition, could result in severe disability and inflict huge economical and public health burden. Its pathogenesis is attributed to multiple etiological factors, including intervertebral disc degeneration (IDD). Emerging evidence suggests that circular RNAs (circRNAs), a major type of regulatory non-coding RNA, play critical roles in cellular processes that are pertinent to IDD development, including nucleus pulposus cell proliferation and apoptosis as well as extracellular matrix deposition. Increasing number of translational studies also indicated that circRNAs could serve as novel biomarkers for the diagnosis of IDD and/or predicting its clinical outcomes. Our review aims to discuss the recent progress in the functions and mechanisms of newly discovered IDD-related circRNAs.

show abstract

A novel identified circ-ANKHD1 targets the miR-27a-3p/SFRP1 signaling pathway and modulates the apoptosis of granulosa cells

Cited by 10 publications

References 23 publications

CircRAB11A act as miR-24-5p sponge promotes proliferation and resists apoptosis of chicken granulosa cell via EGFR/ERK1/2 and RAB11A/ PI3K/AKT pathways

CircRAB11A act as miR-24-5p sponge promotes proliferation and resists apoptosis of chicken granulosa cell via EGFR/ERK1/2 and RAB11A/ PI3K/AKT pathways

Transcriptome analysis reveals pituitary lncRNA, circRNA and mRNA affecting fertility in high- and low-yielding goats

Circular RNAs in Intervertebral Disc Degeneration: An Updated Review

Contact Info

Product

Resources

About