A Novel Multilayer-Coating for Total Knee Arthroplasty Implants is Safe – 10-Year Results From a Randomized-Controlled Trial

Lützner, Jörg; Beyer, Franziska; Lützner, Cornelia; Tille, Eric; Elisabeth, Postler Anne

doi:10.1016/j.arth.2022.07.014

Cited by 6 publications

(1 citation statement)

References 31 publications

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“…In an RCT, a novel multilayer hypoallergenic coating for implants used in TKA was compared with the implants used in standard TKA (both implants consisted of a cobalt, chromium, and molybdenum alloy). However, there were no differences with regard to cumulative 10-year implant survivorship (98% for both) or a relevant increase in metal-ion serum levels 36 . A Level-I study compared 99 patients who underwent a posterior-stabilized TKA with 101 patients who received a cruciate-substituting, medial-stabilized device implanted with kinematic alignment.…”

Section: Implant Designmentioning

confidence: 74%

What’s New in Adult Reconstructive Knee Surgery

Villa,

Hosseinzadeh,

Higuera-Rueda

2023

Journal of Bone and Joint Surgery

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In the current Guest Editorial, we evaluate and summarize the most relevant findings from recent, meaningful, peer-reviewed publications in different research areas. Articles at various Levels of Evidence were included, but increased attention was paid to Level-I and award-winning reports. EconomicsConsiderable debate continues with regard to the economics of reconstructive knee surgery. An updated Medicare projection revealed that, by 2040, the annual number of revision total knee arthroplasties (TKAs) performed would be 115,147, whereas, by 2060, it would be 286,740. These values are important for understanding the future health-care resource utilization involving revision TKA, which is only expected to increase 1 . A secondary analysis of a randomized clinical trial (RCT) evaluating health-care resource utilization up to 12 months after primary TKA, among dissatisfied and satisfied patients, showed that patients dissatisfied with their return to function incurred a mean cost of $19,007.70, compared with $13,523.83 for satisfied patients (p = 0.07). Although the cost difference was not significant, its magnitude deserves attention 2 . Data from the New Zealand Joint Registry indicated that patients undergoing TKA have a mortality rate 8% higher than that of the general population 3 . Assessing mortality after primary TKA is relevant for future economic analyses.

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Section: Implant Designmentioning

confidence: 74%

What’s New in Adult Reconstructive Knee Surgery

Villa,

Hosseinzadeh,

Higuera-Rueda

2023

Journal of Bone and Joint Surgery

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Literature Review to Understand the Burden and Current Non-surgical Management of Moderate–Severe Pain Associated with Knee Osteoarthritis

Castro-Dominguez,

Tibesku,

McAlindon

et al. 2024

Rheumatol Ther

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Introduction:To conduct a literature review exploring the humanistic burden, costs, and guideline recommendations for non-surgical management of moderate-severe pain in knee osteoarthritis (KOA). Methods: Published studies (2018-25 April 2023) assessing the burden of moderate-severe pain in KOA were identified by searching Medline, Embase, EconLit, and Cochrane database, supplemented with grey literature hand searches and reference list snowballing. Treatment guidelines were also identified for key countries. Results: This review included 106 publications and 37 treatment guidelines. Patients with moderate-severe pain were found to experience a low quality of life (QoL) and an impaired ability to perform daily tasks. The economic burden of KOA was substantial, including cost of medical

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