A novel rhodamine-based colorimetric and fluorescent sensor for Hg2+ in water matrix and living cell

A rhodamine-based chemosensor with diphenylselenium for highly selective fluorescence turn-on detection of Hg2+in vitro and in vivo

“…12 Fluorescence chemosensors provide a direct way for mercury detection due to their high sensitivity, selectivity, and their applications in environmental and biological analysis. [13][14][15][16][17][18][19][20][21][22][23][24][25] Among various available uorophores, rhodamine is remarkable due to its exceptional optical properties, such as a long absorption and emission wavelength, high extinction coefficient and quantum yield, and low detection limit. 4,26 Furthermore, rhodamine exists in two forms, a spirolactam (non-uorescent) form and a ring-opened amide (uorescent) form, providing an ideal model for the design of metal ion sensing with light "off-on" switching.…”

Phenothiazine–rhodamine‐based colorimetric and fluorogenic ‘turn‐on' sensor for Zn2+ and bioimaging studies in live cells

“…The characteristic amide carbonyl (C=O) stretching vibrations at 1719 cm −1 shifted to 1684 cm −1 in the presence of Zn 2+ , indicating that the amide spiro‐carbonyl O atom (CO) of the rhodamine B unit was involved in recognition of Zn 2+ . A shift in the carbonyl absorption band in the infrared (IR) region proved to be an effective way to confirm this structural change; this finding was also consistent with that of previous studies. These results strongly supported the involvement of oxygen atoms in the spirolactam amide in Zn 2+ ion binding.…”

A Fluorescent and Colorimetric Chemosensor for Hg2+ Based on Rhodamine 6G With a Two-Step Reaction Mechanism

“…The synthesis of L is outlined in Figure 2. Compound C was synthesized according to the reported procedure (Hong et al, 2016). Compound C (0.5 mmol) and Figure S2) (100 MHz, DMSO) δ 191.…”

“…Compared to other common methods for Hg 2+ detection, fluorescent chemosensors have received considerable attention because of their distinct advantages (Nolna and Lippard, 2008;Zhang et al, 2008;Lee et al, 2015;Xie et al, 2015;He et al, 2016;Sakunkaewkasem et al, 2018;Bai et al, 2019;Yuan et al, 2019). As a result, a growing number of fluorescent chemosensors for Hg 2+ have been reported in the past few decades (Chen et al, 2011;Wang et al, 2012;Park et al, 2013;Cheng et al, 2015;Hong et al, 2016;Lee et al, 2016;Erdemir et al, 2017;Bai et al, 2018;Singh et al, 2018).…”