A novel sandwich-type electrochemical immunosensor for PSA detection based on PtCu bimetallic hybrid (2D/2D) rGO/g-C3N4

Feng, Jinhui; Li, Yueyun; Li, Mingdang; Li, Faying; Han, Jian; Dong, Yunhui; Chen, Zhiwei; Wang, Ping; Liu, Hui; Wei, Qin

doi:10.1016/j.bios.2016.12.070

Cited by 136 publications

(47 citation statements)

References 51 publications

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“…6e g transition, and the Q band is due to the 2a 1u ! 41 The results showed that the modified electrode has a lower resistance than the ITO electrode. This finding is consistent with the previous reports in the literature.…”

Section: Resultsmentioning

confidence: 98%

UV‐Light Photoelectrochemical Sensor Based on the Copper Tetraamino‐Phthalocyanine‐modified ITO Electrode for the Detection of Nifedipine in Drugs and Human Serum

Peng

Zhuge

Huang

et al. 2019

Bulletin Korean Chem Soc

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In this study, a new photoelectrochemical (PEC) sensor based on the copper tetraamino-phthalocyaninemodified ITO electrode (CuTAPc/ITO) was designed for the determination of nifedipine. The prepared CuTAPc materials were characterized using UV-Visible spectrophotometry (UVS), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD). Then, the CuTAPc solution was coated on the ITO electrode surface to fabricate a simple PEC sensing platform. Then, the photoelectrochemical behavior of nifedipine at the CuTAPc/ITO electrode was investigated by chronoamperometry under ultraviolet light irradiation. The obtained results indicated that the modified electrode showed a higher response signal than the blank electrode. The photocurrent of CuTAPc/ITO increased with the increasing concentration of nifedipine. The peak photocurrents were linearly dependent on the nifedipine concentration in the range of 0.25-18.0 μmol/L, thereby providing the detection limit of 0.15 μmol/L (S/N = 3). Due to the good responses for the determination of nifedipine, this sensor can be used as an alternative analysis tool for the detection of nifedipine in various real samples with high sensitivity, low detection limit, and wide linearity range.

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Section: Resultsmentioning

confidence: 98%

UV‐Light Photoelectrochemical Sensor Based on the Copper Tetraamino‐Phthalocyanine‐modified ITO Electrode for the Detection of Nifedipine in Drugs and Human Serum

Peng

Zhuge

Huang

et al. 2019

Bulletin Korean Chem Soc

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“…Feng et al designed an electrochemical immunosensor based on a PtCu hybrid loaded on rGO/g-C 3 N 4 (PtCu@rGO/g-C 3 N 4 ) for the detection of prostate-specific antigen (PSA). [182] Under the optimal conditions (30 min incubation time, 5 mmol/L H 2 O 2 concentration, 2.5 mg/mL PtCu@rGO/g-C 3 N 4 concentration, and pH=7.7 PBS), the response of the designed immunosensor is linearly related to PSA concentrations ranging from 50 fg•mL -1 to 40 ng•mL -1 , and the LOD is as low as 16.6 fg•mL -1 . Zhan et al prepared a g-C 3 N 4 NP-decorated graphene assembly and Co 2 Al layered double hydroxide nanosheets (GR-LDH-C 3 N 4 ) by a simple hydrothermal method and subsequent calcination-recovery process.…”

Section: Co 3 O 4 /Fe 3 O 4 /C-loaded G-c 3 N 4 Nanocompositesmentioning

confidence: 95%

Host–Guest Recognition on 2D Graphitic Carbon Nitride for Nanosensing

Wang

Zhang

et al. 2019

Adv Materials Inter

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In recent years, graphitic carbon nitride (g-C 3 N 4) has attracted much attention due to its unique properties and excellent performance in the field of sensors, which has inspired the authors to compile this review. Although there are many reviews on the synthesis and applications of g-C 3 N 4 materials, a targeted, systematic, comprehensive summary of applications in sensors and the sensing mechanisms of g-C 3 N 4-based nanomaterials have not been published. In this review, the preparation methods and synthetic conditions for preparing g-C 3 N 4 with different morphologies, such as conventional bulk g-C 3 N 4 , g-C 3 N 4 nanosheets, and g-C 3 N 4 quantum dots, are introduced in detail. By reviewing recent advances in g-C 3 N 4-based nanomaterials in ion sensors, biosensors, gas sensors and humidity sensors, this study provides more comprehensive and in-depth information for the further design of g-C 3 N 4based sensors with enhanced performance. A brief outlook of g-C 3 N 4-based sensors is presented as the conclusion of this review.

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“…Adapted from Ref. [54] with permission from Elsevier, copyright (2017) Fig. 11 Simplified ECL mechanism of (a) luminol and (b) Ru(bpy 3 ) 2+ serum samples [62].…”

Section: Psa Detection By Optical Methodsmentioning

confidence: 99%

Detection and monitoring prostate specific antigen using nanotechnology approaches to biosensing

Perry

Cortezon‐Tamarit

Pascu

2019

Front. Chem. Sci. Eng.

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Prostate cancer has a high incidence in men and remains the second cause of mortality due to cancer worldwide. As the development of the disease is greatly correlated to age, the identification of novel detection methods reliable, efficient, and cost effective is a matter of significant importance in the ageing population of western societies. The detection of the prostate specific antigen (PSA) in blood samples has been the preferred method for the detection and monitoring of prostate cancer over the past decades. Despite the indications against its use in massive population screening, PSA still remains the best studied biomarker for prostate cancer and the detection of its different forms and incorporation in multiplexed designs with other biomarkers still remains a highly valuable indicator in the theranostics of prostate cancer. The latest developments in the use of nanomaterials towards the construction of PSA biosensors are reviewed hereby. The incorporation of gold nanoparticles, silica nanoparticles and graphene nanostructures to biosensing devices has represented a big leap forward in terms of sensitivity, stability and miniaturization. Both electrochemical and optical detection methods for the detection of PSA will be reviewed herein.

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A novel sandwich-type electrochemical immunosensor for PSA detection based on PtCu bimetallic hybrid (2D/2D) rGO/g-C3N4

Cited by 136 publications

References 51 publications

UV‐Light Photoelectrochemical Sensor Based on the Copper Tetraamino‐Phthalocyanine‐modified ITO Electrode for the Detection of Nifedipine in Drugs and Human Serum

UV‐Light Photoelectrochemical Sensor Based on the Copper Tetraamino‐Phthalocyanine‐modified ITO Electrode for the Detection of Nifedipine in Drugs and Human Serum

Host–Guest Recognition on 2D Graphitic Carbon Nitride for Nanosensing

Detection and monitoring prostate specific antigen using nanotechnology approaches to biosensing

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