2000
DOI: 10.1039/a908143g
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A novel self-assembled monolayer (SAM) coated microcantilever for low level caesium detection

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Cited by 130 publications
(85 citation statements)
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“…48,49 A much lower concentration of attomolar (∼3 aM) was reported using an analytical multistep method of immuno-PCR. 50 Using labeled reagents, immunoassay coupled with multiphoton detection (IA/MPD) was recently reported to have a detection limit of ∼1 fg/mL for a breast cancer biomarker. 18 For pathogens, although the presence of a single virus particle on a microcantilever was measured 51 in vacuum, the current practice for very dilute samples is tedious.…”
Section: Discussionmentioning
confidence: 99%
“…48,49 A much lower concentration of attomolar (∼3 aM) was reported using an analytical multistep method of immuno-PCR. 50 Using labeled reagents, immunoassay coupled with multiphoton detection (IA/MPD) was recently reported to have a detection limit of ∼1 fg/mL for a breast cancer biomarker. 18 For pathogens, although the presence of a single virus particle on a microcantilever was measured 51 in vacuum, the current practice for very dilute samples is tedious.…”
Section: Discussionmentioning
confidence: 99%
“…Using covalent attachment of mercapto-derivatized macrocyclic cavitands, such as crown ethers, calixarenes, and cyclodextrins, more advanced molecular architectures of biomimetic recep- tors can be formed on gold-coated cantilevers (10,11,18,24). This approach to the situation results in cantilever sensors with remarkably low detection limits.…”
Section: Applicationsmentioning
confidence: 99%
“…This approach to the situation results in cantilever sensors with remarkably low detection limits. In particular, sub-parts-perbillion detection limits for vapors of aromatic compounds and 10 -9 -M concentrations of ionic species in solution were determined (10,11,18). Self-assembly of amino-and carboxy-terminated straight-chain thiols also provides a convenient means to create cantilever sensors that have controllable pH sensitivities (12,27 ).…”
Section: Applicationsmentioning
confidence: 99%
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“…This is partly due to the projected high sensitivity resulting from the large surface area to volume ratio, which greatly amplifies surface effects. Microcantilevers have been shown to detect certain chemical gases in the low ppt level [4][5][6] and recently detect the presence of a few molecules. 7 Furthermore, microcantilevers can inexpensively be manufactured into small arrays containing a very large number of sensors.…”
Section: Introductionmentioning
confidence: 99%