2024
DOI: 10.1007/s10934-024-01685-7
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A novel strategy to produce spherical SBA-15 by polymeric macrospheres as a template for drug delivery

Betzabeth Jaime-Escalante,
Alejandro Rolón-Ávalos,
Luz María Melgoza-Contreras
et al.

Abstract: Mesoporous silica SBA-15 has been a material widely studied for drug delivery due to its high biocompatibility and chemical stability, its ordered mesoporous cavities allow drug loading. However, it has a non-spherical particle shape, making it difficult to use in solid dosage forms, where spherical particles are preferred for better flow and distribution. In this regard, this study presented a novel strategy to produce spheric SBA-15 using polymeric macrospheres of a pharmaceutical grade acidic-resistant copo… Show more

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