A novel“turn-off”fluorescence assay based on acid-copper nanoclusters in deep eutectic solvent micelles for co-aggregation inducing fluorescence enhancement and its application

Chen, Jing; Wang, Yuzhi; Wei, Xiaoxiao; Liu, Ziwei; Xu, Fangting; Li, Heqiong; He, Xiyan

doi:10.1016/j.talanta.2020.121731

Cited by 14 publications

(12 citation statements)

References 36 publications

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“…Such a mechanism has also been observed in different systems in the fluorescence-based sensors. 28,46,47 To explore this indepth, the FT-IR spectra of the probe before and after interaction with the mercaptopurine were studied (Supporting Information). According to the obtained data, the interaction of 6-MP with amine and probably the thiol sites is evident.…”

Section: Optimization Of Parameters For Sensing Processmentioning

confidence: 99%

Intrinsic Dual-Emitting Carbon Quantum-Dot-Based Selective Ratiometric Fluorescent Mercaptopurine Detection

Saboorizadeh

Zare‐Dorabei

2022

ACS Biomater. Sci. Eng.

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, an immunosuppressive drug, has been widely prescribed for treating leukemia and autoimmune diseases. The level of the 6-MP drug in body fluids is of great interest due to the severe health problems related to its overdose. This study used a facile microwave preparation route to synthesize carbon quantum dots (CQDs) using glutathione and formamide as carbon sources. The obtained monodispersed quantum dots showed dual fluorescence emission with a sensitive affinity toward the 6-MP drug. The sensor's response was optimized by tuning the temperature, pH, and volume ratio of the probe. The prepared ratiometric fluorescence method showed accurate measurements for determining mercaptopurine in aqueous solutions in the concentration range of 1.4−7.6 mg L −1 with the limit of detection of 1.3 mg L −1 . The sensor's performance was assessed in complex solutions, human urine, and human plasma sample and recovery values in the range of 88− 127% were obtained. The reliable dual fluorometric sensor showed promising results for 6-MP determination and potential application for the determination of other chemical and biochemical species.

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Section: Optimization Of Parameters For Sensing Processmentioning

confidence: 99%

Intrinsic Dual-Emitting Carbon Quantum-Dot-Based Selective Ratiometric Fluorescent Mercaptopurine Detection

Saboorizadeh

Zare‐Dorabei

2022

ACS Biomater. Sci. Eng.

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“…They also used surfactant-like DES (decyltrimethylammonium bromide + glycerol) to co-aggregate with copper nanoclusters for the detection of iron ions. 20 Moreover, few investigations concerning the use of DES as gelators have also been reported very recently. For instance, Kuroda et al 21 type of DES based on N-methylacetamide and lauric acid as a phase-selective gelator for oil-spill remediation, where the gel phase could be observed at a high DES concentration of 240 mg DES per 1 mL oil.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Wang et al constructed an aqueous micellar two-phase system based on hydrophilic DES (choline chloride + glycerol) and hydrophobic DES (methyltrioctylammonium chloride + PEG 400), where hydrophobic DES can serve as a cationic surfactant to form micelles. They also used surfactant-like DES (decyltrimethylammonium bromide + glycerol) to co-aggregate with copper nanoclusters for the detection of iron ions . Moreover, few investigations concerning the use of DES as gelators have also been reported very recently.…”

Section: Introductionmentioning

confidence: 99%

Amphiphilic Deep Eutectic Solvent Based on Lidocaine and Lauric Acid: Formation of Microemulsion and Gel

Yin

2022

Langmuir

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Deep eutectic solvent (DES), as a new type of promising green solvent, showed great advantages of easy preparation and no need for purification after synthesis and displayed great potential applications in various fields. Herein, we have constructed a new type of therapeutic DES based on lidocaine and lauric acid. The DES displayed good surface activity in constructing a nonaqueous microemulsion with 1,2-propanediol (PG) and isopropyl myristate (IPM) being the polar phase and nonpolar phase, respectively. The obtained nonaqueous microemulsion displayed a structural transition from W/O type to O/W type via a bicontinuous structure with an increase of the PG content. The size, morphology, and microstructure of the microemulsion were explored using dynamic light scattering (DLS), transmission electron microscopy (TEM), and UV–vis absorption spectra measurements. Furthermore, this novel DES can act as a gelator to form a gel in a certain water content range. The rheological measurements suggested the presence of a strong colloidal force. Therefore, the results presented herein were expected to provide a new perspective in the applications of deep eutectic solvent as a surfactant.

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“…Intrinsic fluorescence of NADES represents a novel alternative with great potential for analytical applications, considering their tunability and ability to form organized media. 15 Fluorescence-based detection has been extensively used for the design of sensors and biosensors. 16,17 3D-printable analytical devices have lately attracted much attention from the scientific community due to their enormous advantages, such as low cost, unique portability, quick response, lightweight, flexibility, and, mainly, the possibility of in situ analysis.…”

Section: ■ Introductionmentioning

confidence: 99%

“…To the best of our knowledge, there are no studies about the native fluorescence of NADES, with this property being unknown and unused so far. Intrinsic fluorescence of NADES represents a novel alternative with great potential for analytical applications, considering their tunability and ability to form organized media …”

Section: Introductionmentioning

confidence: 99%

Native Fluorescent Natural Deep Eutectic Solvents for Green Sensing Applications: Curcuminoids in Curcuma longa Powder

Lorenzetti

Vidal

Silva

et al. 2021

ACS Sustainable Chem. Eng.

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Natural deep eutectic solvents are a trending topic in Green Chemistry. These solvents present high solubilization capacity, reusability, tunable properties, simple preparation, biodegradability, safety, high availability, and low cost, making them excellent candidates for analytical applications. In this work, a new family of fluorescent eutectic systems is described, with the fluorescence property being unknown and unused so far. For this purpose, a novel preparation method using an ultrasound probe was employed, by means of an innovative single-step procedure, that included the preparation of FCH (fructose, citric acid, and water, 1:1:5 molar ratio) and the extraction/determination of curcuminoids from Curcuma longa powder. This methodology was successfully carried out by employing a portable and inexpensive 3D-printed fluorometer and a smartphone. In this way, extraction efficiencies between 90 and 106%, relative to the NIST reference method, were obtained in just 3.40 min. Besides, the greenness of the new methodology was evaluated by employing the AGREE metric, showing that the developed approach is >2.5 times greener than previously published works for curcuminoid determination. This groundbreaking procedure is robust, versatile, and simple to implement, does not require sophisticated apparatus or instruments in the detection step, and, mainly, agrees with Green Analytical Chemistry (GAC) principles.

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A novel“turn-off”fluorescence assay based on acid-copper nanoclusters in deep eutectic solvent micelles for co-aggregation inducing fluorescence enhancement and its application

Cited by 14 publications

References 36 publications

Intrinsic Dual-Emitting Carbon Quantum-Dot-Based Selective Ratiometric Fluorescent Mercaptopurine Detection

Intrinsic Dual-Emitting Carbon Quantum-Dot-Based Selective Ratiometric Fluorescent Mercaptopurine Detection

Amphiphilic Deep Eutectic Solvent Based on Lidocaine and Lauric Acid: Formation of Microemulsion and Gel

Native Fluorescent Natural Deep Eutectic Solvents for Green Sensing Applications: Curcuminoids in Curcuma longa Powder

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