A novel voltammetric sensor based on palladium nanoparticles/carbon nanofibers/ionic liquid modified carbon paste electrode for sensitive determination of anti-cancer drug pemetrexed

Afzali, Moslem; Mostafavi, Ali; Nekooie, Reyhaneh; Jahromi, Zahra

doi:10.1016/j.molliq.2019.03.041

Cited by 54 publications

(29 citation statements)

References 41 publications

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“…Afzali et al developed a novel sensor based on Pd/CNF/[M3OA] + [NTF2] − modified CPE through a sensitive square-wave voltammetric procedure for the determination of the anticancer drug pemetrexed. A linear concentration was detected in the range of 1.00–35.0 nM with a detection limit of 0.33 nM by square wave voltammetry (SWV) technique [ 141 ].…”

Section: Nanomaterial-based Biosensors (Nanobiosensors)mentioning

confidence: 99%

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Naresh

Lee

2021

Sensors

1,096

427

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A biosensor is an integrated receptor-transducer device, which can convert a biological response into an electrical signal. The design and development of biosensors have taken a center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications, such as health care and disease diagnosis, environmental monitoring, water and food quality monitoring, and drug delivery. The main challenges involved in the biosensor progress are (i) the efficient capturing of biorecognition signals and the transformation of these signals into electrochemical, electrical, optical, gravimetric, or acoustic signals (transduction process), (ii) enhancing transducer performance i.e., increasing sensitivity, shorter response time, reproducibility, and low detection limits even to detect individual molecules, and (iii) miniaturization of the biosensing devices using micro-and nano-fabrication technologies. Those challenges can be met through the integration of sensing technology with nanomaterials, which range from zero- to three-dimensional, possessing a high surface-to-volume ratio, good conductivities, shock-bearing abilities, and color tunability. Nanomaterials (NMs) employed in the fabrication and nanobiosensors include nanoparticles (NPs) (high stability and high carrier capacity), nanowires (NWs) and nanorods (NRs) (capable of high detection sensitivity), carbon nanotubes (CNTs) (large surface area, high electrical and thermal conductivity), and quantum dots (QDs) (color tunability). Furthermore, these nanomaterials can themselves act as transduction elements. This review summarizes the evolution of biosensors, the types of biosensors based on their receptors, transducers, and modern approaches employed in biosensors using nanomaterials such as NPs (e.g., noble metal NPs and metal oxide NPs), NWs, NRs, CNTs, QDs, and dendrimers and their recent advancement in biosensing technology with the expansion of nanotechnology.

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Section: Nanomaterial-based Biosensors (Nanobiosensors)mentioning

confidence: 99%

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Naresh

Lee

2021

Sensors

1,096

427

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“…Likewise seen for MWCNT-IL nanocomposite, the IL BMIM.PF 6 was the most employed in the nanocomposite mixture, whereas anti-inflammatory and analgesic drugs were the most studied by this type of sensor ( Table 5 ). Among them, carbon nanofibers (CNF) stand out for the preparation of new sensors since they are cheaper than graphene and carbon nanotubes [ 112 , 113 , 114 ]. The same research group has been characterizing the preparation of CNF-based nanocomposites using different ILs [ 112 , 113 , 114 ].…”

Section: (Bio)sensing Strategies For Pharmaceuticals Using Electroche...mentioning

confidence: 99%

(Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools

et al. 2022

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The interaction of carbon-based nanomaterials and ionic liquids (ILs) has been thoroughly exploited for diverse electroanalytical solutions since the first report in 2003. This combination, either through covalent or non-covalent functionalization, takes advantage of the unique characteristics inherent to each material, resulting in synergistic effects that are conferred to the electrochemical (bio)sensing system. From one side, carbon nanomaterials offer miniaturization capacity with enhanced electron transfer rates at a reduced cost, whereas from the other side, ILs contribute as ecological dispersing media for the nanostructures, improving conductivity and biocompatibility. The present review focuses on the use of this interesting type of nanocomposites for the development of (bio)sensors specifically for pharmaceutical detection, with emphasis on the analytical (bio)sensing features. The literature search displayed the conjugation of more than 20 different ILs and several carbon nanomaterials (MWCNT, SWCNT, graphene, carbon nanofibers, fullerene, and carbon quantum dots, among others) that were applied for a large set (about 60) of pharmaceutical compounds. This great variability causes a straightforward comparison between sensors to be a challenging task. Undoubtedly, electrochemical sensors based on the conjugation of carbon nanomaterials with ILs can potentially be established as sustainable analytical tools and viable alternatives to more traditional methods, especially concerning in situ environmental analysis.

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“…Carbon-based metal nanoparticles have attracted considerable attention due to their mechanical and thermal properties and their ability for electrode modifications [13,14]. Because of these properties, metal and metal oxide nanoparticles have been used successfully for increasing carbon paste electrode sensitivity toward various electroanalytical applications [15,16]. It was found in the literature that pure Cu2ONPs [11] and Cu2ONPs supported on carbon materials were applied successfully in different voltametric determinations [17,18].…”

Section: Introductionmentioning

confidence: 99%

Graphite Studded with Facile-Synthesized Cu2O Nanoparticle-Based Cubes as a Novel Electrochemical Sensor for Highly Sensitive Voltametric Determination of Mebeverine Hydrochloride

et al. 2021

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Herein, a feasible chemical reduction method followed by intensive mixing was applied for the preparation of an attractive material based on graphite studded with cuprous oxide nanoparticle-based cubes (Cu2ONPs–C@G). Transmission electron microscope (TEM), scanning electron microscope (SEM), X-ray diffraction (XRD) and cyclic voltammetry (CV) were utilized for characterization. Cuprous oxide nanoparticles (Cu2ONPs), with a diameter range mainly distributed from 4 to 20 nm, aggregate to form microcubes (Cu2ONPs–C) with an average diameter of about 367 nm. Paste electrode was prepared using Cu2ONPs–C@G (Cu2ONPs–C@G/PE) for voltametric quantification of the musculotropic antispasmodic drug: mebeverine hydrochloride (MEB). The electrochemical behavior of MEB was studied using CV, and the optimum analytical parameters were investigated using square wave adsorptive anodic stripping voltammetry (SWAdASV). Moreover, density functional theory (DFT) was used to emphasize the ability of MEB to form a complex with Cu2+, confirming the suggested electrochemical behavior of MEB at Cu2ONPs–C@G/PE. With good stability and high reproducibility, SWAdASV of Cu2ONPs–C@G/PE shows successful quantification of MEB over the concentration range of 5.00 × 10−11–1.10 × 10−9 M with lower limit of detection (LOD) and lower limit of quantification (LOQ) values of 2.41 × 10−11 M and 8.05 × 10−11 M, respectively. Finally, accurate quantification of MEB in dosage forms (tablets) and biological fluids (spiked human urine and plasma samples) was achieved using Cu2ONPs-C@G/PE.

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A novel voltammetric sensor based on palladium nanoparticles/carbon nanofibers/ionic liquid modified carbon paste electrode for sensitive determination of anti-cancer drug pemetrexed

Cited by 54 publications

References 41 publications

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

(Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools

Graphite Studded with Facile-Synthesized Cu2O Nanoparticle-Based Cubes as a Novel Electrochemical Sensor for Highly Sensitive Voltametric Determination of Mebeverine Hydrochloride

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