A nurse-led accelerated procedure for infliximab infusion is well tolerated and effective in patients with inflammatory bowel disease

Nursing‐sensitive outcomes in adult inflammatory bowel disease: A systematic review

“…Of the 18 prospective and cross‐sectional studies, the one of Jelsness‐Jørgensen et al (2012) scored 13 of 13 and the 1 of Holbrook (2007) scored 8 of 13. Two retrospective studies (Lopez et al., 2015; Michielan et al., 2015) scored 8 of 10.…”

“…Three studies were conducted in the Netherlands (de Jong et al., 2017; Linn et al., 2013, 2018). Three in the United Kingdom (Blagden et al, 2015; Holbrook, 2007) and two studies were conducted in Canada (Bernstein et al., 2017; Yongwen Ng et al, 2018), Italy (Michielan et al., 2015; Mocciaro et al., 2017), Australia (Leach et al., 2014; Sack et al., 2012), and Chile (Simian et al., 2017, 2020). Finally, one study was conducted in South Korea (Hwang & Yu, 2019), Greece (Tsoukka et al., 2017), and Norway (Jelsness‐Jørgensen et al., 2012).…”

“…Seventeen of the studies were observational studies (Bernstein et al., 2017; Holbrook, 2007; Hwang & Yu, 2019; Jelsness‐Jørgensen et al., 2012; Leach et al., 2014; Linn et al., 2013; Lopez et al., 2015; Marin‐Jimenez et al., 2019; McCutcheon et al., 2005; Michielan et al., 2015; Mocciaro et al., 2017; Orozco‐Beltran et al., 2019; Sack et al., 2012; Simian et al., 2017, 2020; Tsoukka et al., 2017; Yongwen Ng et al., 2018). Ten were surveys (Bernstein et al., 2017; Holbrook, 2007; Hwang & Yu, 2019; Marin‐Jimenez et al., 2019; McCutcheon et al., 2005; Mocciaro et al., 2017; Orozco‐Beltran et al., 2019; Simian et al., 2017; Tsoukka et al., 2017; Yongwen Ng et al., 2018), two were retrospective (Lopez et al., 2015; Michielan et al., 2015), and five were prospective (Jelsness‐Jørgensen et al., 2012; Leach et al., 2014; Linn et al., 2013; Sack et al., 2012; Simian et al., 2020) in design. Two were prospective interventional studies (Axelrad & Shah, 2016; Cook et al., 2010) and four were RCTs (Del Hoyo et al., 2018; de Jong et al., 2017; Linn et al., 2018; Moss et al., 2010).…”

“…The last identified domain is represented by Patient Satisfaction . Satisfaction as a nursing‐sensitive outcome was analysed in five studies – two RCTs (Del Hoyo et al., 2018; Linn et al., 2018) and three observational studies (Holbrook, 2007; Michielan et al., 2015; Simian et al., 2020) that also had the objective of evaluating patient satisfaction measured by PROMs. The results showed that the assistance of IBD specialist nurses improves the degree of appeasement.…”

“…In terms of the adverse drug reactions outcome, Michielan et al. (2015) retrospectively compared three different nursing regimens adopted for infliximab infusions. In Group 3 (a 1‐hr nurse‐led procedure without routine premedication), there were significantly fewer infusion reactions than in Group 1 (a standard procedure with a 2‐hr infusion, preceded by hydrocortisone medication) (2.2% versus 5.8%, p < 0.001).…”