Integrating biocidal nanoparticles (NPs) into polyamide (PA) membranes shows promise for enhancing resistance to biofouling. Incorporating techniques can tailor thin‐film nanocomposite (TFN) membranes for specific water purification applications. In this study, silver‐based metal–organic framework Ag‐MOFs (using silver nitrate and 1,3,5‐benzentricarboxylic acid as precursors) are incorporated into PA membranes via three different methods: i) incorporation, ii) dip‐coating, and iii) in situ ultrasonic techniques. The characterizations, such as top‐surface and cross‐section scanning and transmission microscopy, reveal that the incorporation methods for the modified TFN membranes substantially control morphology and surface characteristics. For example, the in situ ultrasonically interlayered Ag‐MOFs showed the largest pores (average pore diameter of 14 Å ± 0.1), resulting in the highest water permeance (water flux of 10.9 LMH/bar for Na2SO4). It also show superior antifouling and anti‐biofouling performance, with a flux recovery ratio (FRR) of 94.1% in both fouling tests due to its improved surface hydrophilicity and the antibacterial properties of incorporated Ag‐MOFs. Conversely, the surface‐grafted dip‐coated Ag‐MOFs offered the highest salt rejection, attributed to its highly negatively charged surface and a dense PA network with narrow pores (average pore diameter of 10 Å ± 0.06).